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Items: 1 to 20 of 232

1.

Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome.

He X, Mekasha S, Mavrogiorgos N, Fitzgerald KA, Lien E, Ingalls RR.

J Immunol. 2010 May 15;184(10):5743-54. doi: 10.4049/jimmunol.0903937. Epub 2010 Apr 14.

2.

Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection.

Shimada K, Crother TR, Karlin J, Chen S, Chiba N, Ramanujan VK, Vergnes L, Ojcius DM, Arditi M.

PLoS One. 2011;6(6):e21477. doi: 10.1371/journal.pone.0021477. Epub 2011 Jun 23.

3.

Chlamydia pneumoniae harness host NLRP3 inflammasome-mediated caspase-1 activation for optimal intracellular growth in murine macrophages.

Itoh R, Murakami I, Chou B, Ishii K, Soejima T, Suzuki T, Hiromatsu K.

Biochem Biophys Res Commun. 2014 Sep 26;452(3):689-94. doi: 10.1016/j.bbrc.2014.08.128. Epub 2014 Sep 1.

PMID:
25193701
4.

Synergistic Costimulatory Effect of Chlamydia pneumoniae with Carbon Nanoparticles on NLRP3 Inflammasome-Mediated Interleukin-1β Secretion in Macrophages.

Matsuo J, Nakamura S, Takeda S, Ishida K, Yamazaki T, Yoshida M, Chiba H, Hui SP, Yamaguchi H.

Infect Immun. 2015 Jul;83(7):2917-25. doi: 10.1128/IAI.02968-14. Epub 2015 May 4.

5.

TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection.

Segovia J, Sabbah A, Mgbemena V, Tsai SY, Chang TH, Berton MT, Morris IR, Allen IC, Ting JP, Bose S.

PLoS One. 2012;7(1):e29695. doi: 10.1371/journal.pone.0029695. Epub 2012 Jan 25.

6.

Activation of the Nlrp3 inflammasome by Streptococcus pyogenes requires streptolysin O and NF-kappa B activation but proceeds independently of TLR signaling and P2X7 receptor.

Harder J, Franchi L, Muñoz-Planillo R, Park JH, Reimer T, Núñez G.

J Immunol. 2009 Nov 1;183(9):5823-9. doi: 10.4049/jimmunol.0900444. Epub 2009 Oct 7.

7.

Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome.

Ng J, Hirota SA, Gross O, Li Y, Ulke-Lemee A, Potentier MS, Schenck LP, Vilaysane A, Seamone ME, Feng H, Armstrong GD, Tschopp J, Macdonald JA, Muruve DA, Beck PL.

Gastroenterology. 2010 Aug;139(2):542-52, 552.e1-3. doi: 10.1053/j.gastro.2010.04.005. Epub 2010 Apr 13.

PMID:
20398664
8.

Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation.

Lippai D, Bala S, Petrasek J, Csak T, Levin I, Kurt-Jones EA, Szabo G.

J Leukoc Biol. 2013 Jul;94(1):171-82. doi: 10.1189/jlb.1212659. Epub 2013 Apr 26.

9.

Critical roles of ASC inflammasomes in caspase-1 activation and host innate resistance to Streptococcus pneumoniae infection.

Fang R, Tsuchiya K, Kawamura I, Shen Y, Hara H, Sakai S, Yamamoto T, Fernandes-Alnemri T, Yang R, Hernandez-Cuellar E, Dewamitta SR, Xu Y, Qu H, Alnemri ES, Mitsuyama M.

J Immunol. 2011 Nov 1;187(9):4890-9. doi: 10.4049/jimmunol.1100381. Epub 2011 Sep 28.

10.

TLR agonists stimulate Nlrp3-dependent IL-1β production independently of the purinergic P2X7 receptor in dendritic cells and in vivo.

He Y, Franchi L, Núñez G.

J Immunol. 2013 Jan 1;190(1):334-9. doi: 10.4049/jimmunol.1202737. Epub 2012 Dec 7.

11.

Significant role of IL-1 signaling, but limited role of inflammasome activation, in oviduct pathology during Chlamydia muridarum genital infection.

Nagarajan UM, Sikes JD, Yeruva L, Prantner D.

J Immunol. 2012 Mar 15;188(6):2866-75. doi: 10.4049/jimmunol.1103461. Epub 2012 Feb 13.

12.

Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux.

Karmakar M, Katsnelson M, Malak HA, Greene NG, Howell SJ, Hise AG, Camilli A, Kadioglu A, Dubyak GR, Pearlman E.

J Immunol. 2015 Feb 15;194(4):1763-75. doi: 10.4049/jimmunol.1401624. Epub 2015 Jan 21.

13.

NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways.

Willingham SB, Allen IC, Bergstralh DT, Brickey WJ, Huang MT, Taxman DJ, Duncan JA, Ting JP.

J Immunol. 2009 Aug 1;183(3):2008-15. doi: 10.4049/jimmunol.0900138. Epub 2009 Jul 8.

14.

Polyene macrolide antifungal drugs trigger interleukin-1β secretion by activating the NLRP3 inflammasome.

Darisipudi MN, Allam R, Rupanagudi KV, Anders HJ.

PLoS One. 2011;6(5):e19588. doi: 10.1371/journal.pone.0019588. Epub 2011 May 23.

15.

Critical role for the AIM2 inflammasome during acute CNS bacterial infection.

Hanamsagar R, Aldrich A, Kielian T.

J Neurochem. 2014 May;129(4):704-11. doi: 10.1111/jnc.12669. Epub 2014 Feb 19.

16.

NLRP3 Is a Critical Regulator of Inflammation and Innate Immune Cell Response during Mycoplasma pneumoniae Infection.

Segovia JA, Chang TH, Winter VT, Coalson JJ, Cagle MP, Pandranki L, Bose S, Baseman JB, Kannan TR.

Infect Immun. 2017 Dec 19;86(1). pii: e00548-17. doi: 10.1128/IAI.00548-17. Print 2018 Jan.

17.

Doxorubicin and daunorubicin induce processing and release of interleukin-1β through activation of the NLRP3 inflammasome.

Sauter KA, Wood LJ, Wong J, Iordanov M, Magun BE.

Cancer Biol Ther. 2011 Jun 15;11(12):1008-16. Epub 2011 Jun 15.

18.

Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3.

Oosting M, Buffen K, Malireddi SR, Sturm P, Verschueren I, Koenders MI, van de Veerdonk FL, van der Meer JW, Netea MG, Kanneganti TD, Joosten LA.

Arthritis Res Ther. 2012 Nov 13;14(6):R247. doi: 10.1186/ar4090.

19.

The NLRP3/ASC inflammasome promotes T-cell-dependent immune complex glomerulonephritis by canonical and noncanonical mechanisms.

Andersen K, Eltrich N, Lichtnekert J, Anders HJ, Vielhauer V.

Kidney Int. 2014 Nov;86(5):965-78. doi: 10.1038/ki.2014.161. Epub 2014 May 7.

20.

Inflammasome activation and IL-1β/IL-18 processing are influenced by distinct pathways in microglia.

Hanamsagar R, Torres V, Kielian T.

J Neurochem. 2011 Nov;119(4):736-48. doi: 10.1111/j.1471-4159.2011.07481.x. Epub 2011 Oct 11.

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