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Items: 1 to 20 of 73

1.

Targeting Robo4-dependent Slit signaling to survive the cytokine storm in sepsis and influenza.

London NR, Zhu W, Bozza FA, Smith MC, Greif DM, Sorensen LK, Chen L, Kaminoh Y, Chan AC, Passi SF, Day CW, Barnard DL, Zimmerman GA, Krasnow MA, Li DY.

Sci Transl Med. 2010 Mar 17;2(23):23ra19. doi: 10.1126/scitranslmed.3000678.

2.

Robo4-dependent Slit signaling stabilizes the vasculature during pathologic angiogenesis and cytokine storm.

London NR, Li DY.

Curr Opin Hematol. 2011 May;18(3):186-90. doi: 10.1097/MOH.0b013e328345a4b9. Review.

3.

Quelling the storm: utilization of sphingosine-1-phosphate receptor signaling to ameliorate influenza virus-induced cytokine storm.

Walsh KB, Teijaro JR, Rosen H, Oldstone MB.

Immunol Res. 2011 Oct;51(1):15-25. doi: 10.1007/s12026-011-8240-z. Review.

PMID:
21901448
4.

Apolipoprotein A-I mimetic peptide 4F attenuates kidney injury, heart injury, and endothelial dysfunction in sepsis.

Moreira RS, Irigoyen M, Sanches TR, Volpini RA, Camara NO, Malheiros DM, Shimizu MH, Seguro AC, Andrade L.

Am J Physiol Regul Integr Comp Physiol. 2014 Sep 1;307(5):R514-24. doi: 10.1152/ajpregu.00445.2013. Epub 2014 Jun 11.

5.

Influenza virus NS1 protein protects against lymphohematopoietic pathogenesis in an in vivo mouse model.

Hyland L, Webby R, Sandbulte MR, Clarke B, Hou S.

Virology. 2006 May 25;349(1):156-63. Epub 2006 Mar 20.

6.

Sepsis and endothelial permeability.

Lee WL, Slutsky AS.

N Engl J Med. 2010 Aug 12;363(7):689-91. doi: 10.1056/NEJMcibr1007320. No abstract available.

PMID:
20818861
7.

Slit2/Robo4 signaling pathway modulates endothelial hyper-permeability in a two-event in vitro model of transfusion-related acute lung injury.

Weng J, Zhou X, Xie H, Gao Y, Wang Z, Gong Y.

Blood Cells Mol Dis. 2019 May;76:7-12. doi: 10.1016/j.bcmd.2018.11.003. Epub 2018 Nov 13.

PMID:
30846360
8.

Slit2-Robo4 pathway modulates lipopolysaccharide-induced endothelial inflammation and its expression is dysregulated during endotoxemia.

Zhao H, Anand AR, Ganju RK.

J Immunol. 2014 Jan 1;192(1):385-93. doi: 10.4049/jimmunol.1302021. Epub 2013 Nov 22.

9.

Robo4 maintains vessel integrity and inhibits angiogenesis by interacting with UNC5B.

Koch AW, Mathivet T, Larrivée B, Tong RK, Kowalski J, Pibouin-Fragner L, Bouvrée K, Stawicki S, Nicholes K, Rathore N, Scales SJ, Luis E, del Toro R, Freitas C, Bréant C, Michaud A, Corvol P, Thomas JL, Wu Y, Peale F, Watts RJ, Tessier-Lavigne M, Bagri A, Eichmann A.

Dev Cell. 2011 Jan 18;20(1):33-46. doi: 10.1016/j.devcel.2010.12.001.

10.

Plexin-A4-semaphorin 3A signaling is required for Toll-like receptor- and sepsis-induced cytokine storm.

Wen H, Lei Y, Eun SY, Ting JP.

J Exp Med. 2010 Dec 20;207(13):2943-57. doi: 10.1084/jem.20101138. Epub 2010 Nov 22.

11.

Expression of inflammation-related genes in the lung of BALB/c mice response to H7N9 influenza A virus with different pathogenicity.

Yu M, Wang Q, Qi W, Zhang K, Liu J, Tao P, Ge S, Liao M, Ning Z.

Med Microbiol Immunol. 2016 Oct;205(5):501-9. doi: 10.1007/s00430-016-0466-x. Epub 2016 Jul 11.

PMID:
27401907
12.

Slit2-Robo4 signalling promotes vascular stability by blocking Arf6 activity.

Jones CA, Nishiya N, London NR, Zhu W, Sorensen LK, Chan AC, Lim CJ, Chen H, Zhang Q, Schultz PG, Hayallah AM, Thomas KR, Famulok M, Zhang K, Ginsberg MH, Li DY.

Nat Cell Biol. 2009 Nov;11(11):1325-31. doi: 10.1038/ncb1976. Epub 2009 Oct 18.

13.

Soluble Robo4 receptor inhibits in vivo angiogenesis and endothelial cell migration.

Suchting S, Heal P, Tahtis K, Stewart LM, Bicknell R.

FASEB J. 2005 Jan;19(1):121-3. Epub 2004 Oct 14.

PMID:
15486058
14.

Mice lacking both TNF and IL-1 receptors exhibit reduced lung inflammation and delay in onset of death following infection with a highly virulent H5N1 virus.

Perrone LA, Szretter KJ, Katz JM, Mizgerd JP, Tumpey TM.

J Infect Dis. 2010 Oct 15;202(8):1161-70. doi: 10.1086/656365.

15.

Influenza virus-cytokine-protease cycle in the pathogenesis of vascular hyperpermeability in severe influenza.

Wang S, Le TQ, Kurihara N, Chida J, Cisse Y, Yano M, Kido H.

J Infect Dis. 2010 Oct 1;202(7):991-1001. doi: 10.1086/656044.

PMID:
20731583
16.

Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection.

Teijaro JR, Walsh KB, Cahalan S, Fremgen DM, Roberts E, Scott F, Martinborough E, Peach R, Oldstone MB, Rosen H.

Cell. 2011 Sep 16;146(6):980-91. doi: 10.1016/j.cell.2011.08.015.

17.

Suppression of Slit2/Robo1 mediated HUVEC migration by Robo4.

Enomoto S, Mitsui K, Kawamura T, Iwanari H, Daigo K, Horiuchi K, Minami T, Kodama T, Hamakubo T.

Biochem Biophys Res Commun. 2016 Jan 22;469(4):797-802. doi: 10.1016/j.bbrc.2015.12.075. Epub 2015 Dec 20.

PMID:
26713366
18.

Involvement of toll-like receptor 3 in the immune response of lung epithelial cells to double-stranded RNA and influenza A virus.

Guillot L, Le Goffic R, Bloch S, Escriou N, Akira S, Chignard M, Si-Tahar M.

J Biol Chem. 2005 Feb 18;280(7):5571-80. Epub 2004 Dec 3.

19.

Targeting the TLR co-receptor CD14 with TLR2-derived peptides modulates immune responses to pathogens.

Raby AC, Holst B, Le Bouder E, Diaz C, Ferran E, Conraux L, Guillemot JC, Coles B, Kift-Morgan A, Colmont CS, Szakmany T, Ferrara P, Hall JE, Topley N, Labéta MO.

Sci Transl Med. 2013 May 15;5(185):185ra64. doi: 10.1126/scitranslmed.3005544.

20.

Antiviral activity of the proteasome inhibitor VL-01 against influenza A viruses.

Haasbach E, Pauli EK, Spranger R, Mitzner D, Schubert U, Kircheis R, Planz O.

Antiviral Res. 2011 Sep;91(3):304-13. doi: 10.1016/j.antiviral.2011.07.006. Epub 2011 Jul 13.

PMID:
21777621

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