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Items: 1 to 20 of 227

1.

Helicobacter pylori-induced activation of beta-catenin involves low density lipoprotein receptor-related protein 6 and Dishevelled.

Gnad T, Feoktistova M, Leverkus M, Lendeckel U, Naumann M.

Mol Cancer. 2010 Feb 5;9:31. doi: 10.1186/1476-4598-9-31.

2.

Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions.

Zeng X, Huang H, Tamai K, Zhang X, Harada Y, Yokota C, Almeida K, Wang J, Doble B, Woodgett J, Wynshaw-Boris A, Hsieh JC, He X.

Development. 2008 Jan;135(2):367-75. Epub 2007 Dec 12.

3.

LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin.

Cselenyi CS, Jernigan KK, Tahinci E, Thorne CA, Lee LA, Lee E.

Proc Natl Acad Sci U S A. 2008 Jun 10;105(23):8032-7. doi: 10.1073/pnas.0803025105. Epub 2008 May 28.

4.

Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction.

Gan XQ, Wang JY, Xi Y, Wu ZL, Li YP, Li L.

J Cell Biol. 2008 Mar 24;180(6):1087-100. doi: 10.1083/jcb.200710050. Epub 2008 Mar 17.

5.

Quantitative and kinetic profile of Wnt/β-catenin signaling components during human neural progenitor cell differentiation.

Mazemondet O, Hubner R, Frahm J, Koczan D, Bader BM, Weiss DG, Uhrmacher AM, Frech MJ, Rolfs A, Luo J.

Cell Mol Biol Lett. 2011 Dec;16(4):515-38. doi: 10.2478/s11658-011-0021-0. Epub 2011 Jul 29.

PMID:
21805133
6.

Helicobacter pylori upregulates Nanog and Oct4 via Wnt/β-catenin signaling pathway to promote cancer stem cell-like properties in human gastric cancer.

Yong X, Tang B, Xiao YF, Xie R, Qin Y, Luo G, Hu CJ, Dong H, Yang SM.

Cancer Lett. 2016 May 1;374(2):292-303. doi: 10.1016/j.canlet.2016.02.032. Epub 2016 Mar 2.

7.

Parathyroid hormone receptor directly interacts with dishevelled to regulate beta-Catenin signaling and osteoclastogenesis.

Romero G, Sneddon WB, Yang Y, Wheeler D, Blair HC, Friedman PA.

J Biol Chem. 2010 May 7;285(19):14756-63. doi: 10.1074/jbc.M110.102970. Epub 2010 Mar 8.

8.

Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation.

Bilic J, Huang YL, Davidson G, Zimmermann T, Cruciat CM, Bienz M, Niehrs C.

Science. 2007 Jun 15;316(5831):1619-22.

9.

Niclosamide suppresses cancer cell growth by inducing Wnt co-receptor LRP6 degradation and inhibiting the Wnt/β-catenin pathway.

Lu W, Lin C, Roberts MJ, Waud WR, Piazza GA, Li Y.

PLoS One. 2011;6(12):e29290. doi: 10.1371/journal.pone.0029290. Epub 2011 Dec 16.

10.

Interaction of MUC1 with beta-catenin modulates the Wnt target gene cyclinD1 in H. pylori-induced gastric cancer.

Udhayakumar G, Jayanthi V, Devaraj N, Devaraj H.

Mol Carcinog. 2007 Sep;46(9):807-17.

PMID:
17393422
11.

Differential mediation of the Wnt canonical pathway by mammalian Dishevelleds-1, -2, and -3.

Lee YN, Gao Y, Wang HY.

Cell Signal. 2008 Feb;20(2):443-52. Epub 2007 Nov 17.

12.

Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin.

González-Sancho JM, Brennan KR, Castelo-Soccio LA, Brown AM.

Mol Cell Biol. 2004 Jun;24(11):4757-68.

13.

Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression.

Nam JS, Turcotte TJ, Smith PF, Choi S, Yoon JK.

J Biol Chem. 2006 May 12;281(19):13247-57. Epub 2006 Mar 16.

14.

Protease-activated receptor-1 (PAR1) acts via a novel Galpha13-dishevelled axis to stabilize beta-catenin levels.

Turm H, Maoz M, Katz V, Yin YJ, Offermanns S, Bar-Shavit R.

J Biol Chem. 2010 May 14;285(20):15137-48. doi: 10.1074/jbc.M109.072843. Epub 2010 Mar 11.

15.

β-arrestin promotes Wnt-induced low density lipoprotein receptor-related protein 6 (Lrp6) phosphorylation via increased membrane recruitment of Amer1 protein.

Kríz V, Pospíchalová V, Masek J, Kilander MB, Slavík J, Tanneberger K, Schulte G, Machala M, Kozubík A, Behrens J, Bryja V.

J Biol Chem. 2014 Jan 10;289(2):1128-41. doi: 10.1074/jbc.M113.498444. Epub 2013 Nov 21.

16.

Sequential activation and inactivation of Dishevelled in the Wnt/beta-catenin pathway by casein kinases.

Bernatik O, Ganji RS, Dijksterhuis JP, Konik P, Cervenka I, Polonio T, Krejci P, Schulte G, Bryja V.

J Biol Chem. 2011 Mar 25;286(12):10396-410. doi: 10.1074/jbc.M110.169870. Epub 2011 Feb 1.

17.

Prickle-1 negatively regulates Wnt/beta-catenin pathway by promoting Dishevelled ubiquitination/degradation in liver cancer.

Chan DW, Chan CY, Yam JW, Ching YP, Ng IO.

Gastroenterology. 2006 Oct;131(4):1218-27. Epub 2006 Jul 24.

PMID:
17030191
18.

LRP6 mediates Wnt/β-catenin signaling and regulates adipogenic differentiation in human mesenchymal stem cells.

Peröbner I, Karow M, Jochum M, Neth P.

Int J Biochem Cell Biol. 2012 Nov;44(11):1970-82. doi: 10.1016/j.biocel.2012.07.025. Epub 2012 Aug 2.

PMID:
22871567
19.

The pseudoreceptor BMP and activin membrane-bound inhibitor positively modulates Wnt/beta-catenin signaling.

Lin Z, Gao C, Ning Y, He X, Wu W, Chen YG.

J Biol Chem. 2008 Nov 28;283(48):33053-8. doi: 10.1074/jbc.M804039200. Epub 2008 Oct 6.

20.

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