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Items: 1 to 20 of 96

1.

A single polymorphic amino acid on Toxoplasma gondii kinase ROP16 determines the direct and strain-specific activation of Stat3.

Yamamoto M, Standley DM, Takashima S, Saiga H, Okuyama M, Kayama H, Kubo E, Ito H, Takaura M, Matsuda T, Soldati-Favre D, Takeda K.

J Exp Med. 2009 Nov 23;206(12):2747-60. doi: 10.1084/jem.20091703. Epub 2009 Nov 9.

2.

Toxoplasma gondii rhoptry kinase ROP16 activates STAT3 and STAT6 resulting in cytokine inhibition and arginase-1-dependent growth control.

Butcher BA, Fox BA, Rommereim LM, Kim SG, Maurer KJ, Yarovinsky F, Herbert DR, Bzik DJ, Denkers EY.

PLoS Pathog. 2011 Sep;7(9):e1002236. doi: 10.1371/journal.ppat.1002236. Epub 2011 Sep 8.

3.

Toxoplasma rhoptry protein 16 (ROP16) subverts host function by direct tyrosine phosphorylation of STAT6.

Ong YC, Reese ML, Boothroyd JC.

J Biol Chem. 2010 Sep 10;285(37):28731-40. doi: 10.1074/jbc.M110.112359. Epub 2010 Jul 12.

4.

IL-10-independent STAT3 activation by Toxoplasma gondii mediates suppression of IL-12 and TNF-alpha in host macrophages.

Butcher BA, Kim L, Panopoulos AD, Watowich SS, Murray PJ, Denkers EY.

J Immunol. 2005 Mar 15;174(6):3148-52.

5.
6.

IL-10 is not required to prevent immune hyperactivity during memory responses to Toxoplasma gondii.

Wille U, Nishi M, Lieberman L, Wilson EH, Roos DS, Hunter CA.

Parasite Immunol. 2004 May;26(5):229-36.

7.

Toxoplasma gondii rhoptry 16 kinase promotes host resistance to oral infection and intestinal inflammation only in the context of the dense granule protein GRA15.

Jensen KD, Hu K, Whitmarsh RJ, Hassan MA, Julien L, Lu D, Chen L, Hunter CA, Saeij JP.

Infect Immun. 2013 Jun;81(6):2156-67. doi: 10.1128/IAI.01185-12. Epub 2013 Apr 1.

8.

Targeted disruption of CK1α in Toxoplasma gondii increases acute virulence in mice.

Wang Z, Wang S, Wang W, Gu Y, Liu H, Wei F, Liu Q.

Eur J Protistol. 2016 Oct;56:90-101. doi: 10.1016/j.ejop.2016.07.006. Epub 2016 Aug 4.

PMID:
27567091
9.

Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation.

Jensen KD, Wang Y, Wojno ED, Shastri AJ, Hu K, Cornel L, Boedec E, Ong YC, Chien YH, Hunter CA, Boothroyd JC, Saeij JP.

Cell Host Microbe. 2011 Jun 16;9(6):472-83. doi: 10.1016/j.chom.2011.04.015.

10.
11.

Production of IL-12 by macrophages infected with Toxoplasma gondii depends on the parasite genotype.

Robben PM, Mordue DG, Truscott SM, Takeda K, Akira S, Sibley LD.

J Immunol. 2004 Mar 15;172(6):3686-94.

12.

Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells.

Scanga CA, Aliberti J, Jankovic D, Tilloy F, Bennouna S, Denkers EY, Medzhitov R, Sher A.

J Immunol. 2002 Jun 15;168(12):5997-6001.

13.

T cell response mediated by myeloid cell-derived IL-12 is responsible for Porphyromonas gingivalis-induced periodontitis in IL-10-deficient mice.

Sasaki H, Suzuki N, Kent R Jr, Kawashima N, Takeda J, Stashenko P.

J Immunol. 2008 May 1;180(9):6193-8.

14.

The NF-kappa B family member RelB is required for innate and adaptive immunity to Toxoplasma gondii.

Caamaño J, Alexander J, Craig L, Bravo R, Hunter CA.

J Immunol. 1999 Oct 15;163(8):4453-61.

15.

Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue.

Saeij JP, Coller S, Boyle JP, Jerome ME, White MW, Boothroyd JC.

Nature. 2007 Jan 18;445(7125):324-7. Epub 2006 Dec 20.

16.

Identification of STAT4-dependent and independent mechanisms of resistance to Toxoplasma gondii.

Cai G, Radzanowski T, Villegas EN, Kastelein R, Hunter CA.

J Immunol. 2000 Sep 1;165(5):2619-27.

17.

Both lymphotoxin-alpha and TNF are crucial for control of Toxoplasma gondii in the central nervous system.

Schlüter D, Kwok LY, Lütjen S, Soltek S, Hoffmann S, Körner H, Deckert M.

J Immunol. 2003 Jun 15;170(12):6172-82.

18.

Toxoplasma gondii genotype determines MyD88-dependent signaling in infected macrophages.

Kim L, Butcher BA, Lee CW, Uematsu S, Akira S, Denkers EY.

J Immunol. 2006 Aug 15;177(4):2584-91.

19.

Roles of Toxoplasma gondii-derived heat shock protein 70 in host defense against T. gondii infection.

Ahmed AK, Mun HS, Aosai F, Piao LX, Fang H, Norose K, Yano A.

Microbiol Immunol. 2004;48(11):911-5.

20.

IL-23 provides a limited mechanism of resistance to acute toxoplasmosis in the absence of IL-12.

Lieberman LA, Cardillo F, Owyang AM, Rennick DM, Cua DJ, Kastelein RA, Hunter CA.

J Immunol. 2004 Aug 1;173(3):1887-93.

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