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Items: 1 to 20 of 62

1.

Suppression of a pro-apoptotic K+ channel as a mechanism for hepatitis C virus persistence.

Mankouri J, Dallas ML, Hughes ME, Griffin SD, Macdonald A, Peers C, Harris M.

Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15903-8. doi: 10.1073/pnas.0906798106. Epub 2009 Aug 26.

2.

Hepatitis C virus NS5A inhibits mixed lineage kinase 3 to block apoptosis.

Amako Y, Igloi Z, Mankouri J, Kazlauskas A, Saksela K, Dallas M, Peers C, Harris M.

J Biol Chem. 2013 Aug 23;288(34):24753-63. doi: 10.1074/jbc.M113.491985. Epub 2013 Jul 15.

3.

Induced oxidative stress and activated expression of manganese superoxide dismutase during hepatitis C virus replication: role of JNK, p38 MAPK and AP-1.

Qadri I, Iwahashi M, Capasso JM, Hopken MW, Flores S, Schaack J, Simon FR.

Biochem J. 2004 Mar 15;378(Pt 3):919-28. Erratum in: Biochem J. 2004 Jul 1;381(Pt 3):951.

4.

Critical role of Casein kinase 2 in hepatitis C NS5A-mediated inhibition of Kv2.1 K(+) channel function.

Clemens K, Yeh CY, Aizenman E.

Neurosci Lett. 2015 Nov 16;609:48-52. doi: 10.1016/j.neulet.2015.10.021. Epub 2015 Oct 17.

5.

Carbon monoxide protects against oxidant-induced apoptosis via inhibition of Kv2.1.

Dallas ML, Boyle JP, Milligan CJ, Sayer R, Kerrigan TL, McKinstry C, Lu P, Mankouri J, Harris M, Scragg JL, Pearson HA, Peers C.

FASEB J. 2011 May;25(5):1519-30. doi: 10.1096/fj.10-173450. Epub 2011 Jan 19.

PMID:
21248240
6.

Regulation of neuronal proapoptotic potassium currents by the hepatitis C virus nonstructural protein 5A.

Norris CA, He K, Springer MG, Hartnett KA, Horn JP, Aizenman E.

J Neurosci. 2012 Jun 27;32(26):8865-70. doi: 10.1523/JNEUROSCI.0937-12.2012.

7.
8.

Apoptotic surge of potassium currents is mediated by p38 phosphorylation of Kv2.1.

Redman PT, He K, Hartnett KA, Jefferson BS, Hu L, Rosenberg PA, Levitan ES, Aizenman E.

Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3568-73. Epub 2007 Feb 20.

9.

Establishment of a subgenomic replicon for bovine viral diarrhea virus in Huh-7 cells and modulation of interferon-regulated factor 3-mediated antiviral response.

Horscroft N, Bellows D, Ansari I, Lai VC, Dempsey S, Liang D, Donis R, Zhong W, Hong Z.

J Virol. 2005 Mar;79(5):2788-96.

10.

The regulation of hepatitis C virus (HCV) internal ribosome-entry site-mediated translation by HCV replicons and nonstructural proteins.

He Y, Yan W, Coito C, Li Y, Gale M Jr, Katze MG.

J Gen Virol. 2003 Mar;84(Pt 3):535-43.

PMID:
12604803
11.

Hepatitis C virus-induced activation of β-catenin promotes c-Myc expression and a cascade of pro-carcinogenetic events.

Higgs MR, Lerat H, Pawlotsky JM.

Oncogene. 2013 Sep 26;32(39):4683-93. doi: 10.1038/onc.2012.484. Epub 2012 Oct 29.

PMID:
23108410
12.

p38 activation is required upstream of potassium current enhancement and caspase cleavage in thiol oxidant-induced neuronal apoptosis.

McLaughlin B, Pal S, Tran MP, Parsons AA, Barone FC, Erhardt JA, Aizenman E.

J Neurosci. 2001 May 15;21(10):3303-11.

13.

Apolipoprotein J, a glucose-upregulated molecular chaperone, stabilizes core and NS5A to promote infectious hepatitis C virus virion production.

Lin CC, Tsai P, Sun HY, Hsu MC, Lee JC, Wu IC, Tsao CW, Chang TT, Young KC.

J Hepatol. 2014 Nov;61(5):984-93. doi: 10.1016/j.jhep.2014.06.026. Epub 2014 Jul 1.

PMID:
24996046
14.

Regulation of hepatitis C virus replication by nuclear translocation of nonstructural 5A protein and transcriptional activation of host genes.

Maqbool MA, Imache MR, Higgs MR, Carmouse S, Pawlotsky JM, Lerat H.

J Virol. 2013 May;87(10):5523-39. doi: 10.1128/JVI.00585-12. Epub 2013 Mar 6. Erratum in: J Virol. 2013 Sep;87(17):9963.

15.

Distinct modifications in Kv2.1 channel via chemokine receptor CXCR4 regulate neuronal survival-death dynamics.

Shepherd AJ, Loo L, Gupte RP, Mickle AD, Mohapatra DP.

J Neurosci. 2012 Dec 5;32(49):17725-39. doi: 10.1523/JNEUROSCI.3029-12.2012.

16.

Non-structural protein 4A of Hepatitis C virus accumulates on mitochondria and renders the cells prone to undergoing mitochondria-mediated apoptosis.

Nomura-Takigawa Y, Nagano-Fujii M, Deng L, Kitazawa S, Ishido S, Sada K, Hotta H.

J Gen Virol. 2006 Jul;87(Pt 7):1935-45.

PMID:
16760395
17.

Convergent Ca2+ and Zn2+ signaling regulates apoptotic Kv2.1 K+ currents.

McCord MC, Aizenman E.

Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13988-93. doi: 10.1073/pnas.1306238110. Epub 2013 Aug 5.

18.

Studies on the role of NS3 and NS5A non-structural genes of hepatitis C virus genotype 3a local isolates in apoptosis.

Sabri S, Idrees M, Rafique S, Ali A, Iqbal M.

Int J Infect Dis. 2014 Aug;25:38-44. doi: 10.1016/j.ijid.2014.01.010. Epub 2014 May 17.

19.

Calpain activation by hepatitis C virus proteins inhibits the extrinsic apoptotic signaling pathway.

Simonin Y, Disson O, Lerat H, Antoine E, Binamé F, Rosenberg AR, Desagher S, Lassus P, Bioulac-Sage P, Hibner U.

Hepatology. 2009 Nov;50(5):1370-9. doi: 10.1002/hep.23169.

PMID:
19711428
20.

Transient replication of a hepatitis C virus genotype 1b replicon chimera encoding NS5A-5B from genotype 3a.

Kylefjord H, Danielsson A, Sedig S, Belda O, Wiktelius D, Vrang L, Targett-Adams P.

J Virol Methods. 2014 Jan;195:156-63. doi: 10.1016/j.jviromet.2013.09.017. Epub 2013 Oct 10.

PMID:
24120570

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