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Items: 1 to 20 of 65

1.

Proteomics analysis of mitochondrial proteins reveals overexpression of a mitochondrial protein chaperon, prohibitin, in cells expressing hepatitis C virus core protein.

Tsutsumi T, Matsuda M, Aizaki H, Moriya K, Miyoshi H, Fujie H, Shintani Y, Yotsuyanagi H, Miyamura T, Suzuki T, Koike K.

Hepatology. 2009 Aug;50(2):378-86. doi: 10.1002/hep.22998.

PMID:
19591124
2.

Mitochondrial injury, oxidative stress, and antioxidant gene expression are induced by hepatitis C virus core protein.

Okuda M, Li K, Beard MR, Showalter LA, Scholle F, Lemon SM, Weinman SA.

Gastroenterology. 2002 Feb;122(2):366-75.

PMID:
11832451
3.

Hepatitis C virus core protein inhibits mitochondrial electron transport and increases reactive oxygen species (ROS) production.

Korenaga M, Wang T, Li Y, Showalter LA, Chan T, Sun J, Weinman SA.

J Biol Chem. 2005 Nov 11;280(45):37481-8. Epub 2005 Sep 8.

4.

Prohibitin is overexpressed in Huh-7-HCV and Huh-7.5-HCV cells harboring in vitro transcribed full-length hepatitis C virus RNA.

Dang SS, Sun MZ, Yang E, Xun M, Ma L, Jia ZS, Wang WJ, Jia XL.

Virol J. 2011 Sep 6;8:424. doi: 10.1186/1743-422X-8-424.

5.

S-adenosylmethionine prevents chronic alcohol-induced mitochondrial dysfunction in the rat liver.

Bailey SM, Robinson G, Pinner A, Chamlee L, Ulasova E, Pompilius M, Page GP, Chhieng D, Jhala N, Landar A, Kharbanda KK, Ballinger S, Darley-Usmar V.

Am J Physiol Gastrointest Liver Physiol. 2006 Nov;291(5):G857-67. Epub 2006 Jul 6.

6.

Hepatocarcinogenesis in hepatitis C: HCV shrewdly exacerbates oxidative stress by modulating both production and scavenging of reactive oxygen species.

Fujinaga H, Tsutsumi T, Yotsuyanagi H, Moriya K, Koike K.

Oncology. 2011;81 Suppl 1:11-7. doi: 10.1159/000333253. Epub 2011 Dec 22.

PMID:
22212930
7.

Causes and consequences of mitochondrial reactive oxygen species generation in hepatitis C.

Wang T, Weinman SA.

J Gastroenterol Hepatol. 2006 Oct;21 Suppl 3:S34-7. Review.

PMID:
16958669
8.

Acute expression of hepatitis C core protein in adult mouse liver: Mitochondrial stress and apoptosis.

Chang ML, Chen JC, Chang MY, Yeh CT, Lin WP, Liang CK, Huang SF, Dang KN, Chiu CT, Lin DY.

Scand J Gastroenterol. 2008;43(6):747-55. doi: 10.1080/00365520701875987.

PMID:
18569993
9.

Hepatitis C virus core protein, cytochrome P450 2E1, and alcohol produce combined mitochondrial injury and cytotoxicity in hepatoma cells.

Otani K, Korenaga M, Beard MR, Li K, Qian T, Showalter LA, Singh AK, Wang T, Weinman SA.

Gastroenterology. 2005 Jan;128(1):96-107.

PMID:
15633127
10.

Mitochondrial dysfunction in hepatitis C.

Korenaga M, Okuda M, Otani K, Wang T, Li Y, Weinman SA.

J Clin Gastroenterol. 2005 Apr;39(4 Suppl 2):S162-6. Review.

PMID:
15758653
11.

Characterization of liver histopathology in a transgenic mouse model expressing genotype 1a hepatitis C virus core and envelope proteins 1 and 2.

Naas T, Ghorbani M, Alvarez-Maya I, Lapner M, Kothary R, De Repentigny Y, Gomes S, Babiuk L, Giulivi A, Soare C, Azizi A, Diaz-Mitoma F.

J Gen Virol. 2005 Aug;86(Pt 8):2185-96.

PMID:
16033966
12.

Oxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocarcinogenesis.

Moriya K, Nakagawa K, Santa T, Shintani Y, Fujie H, Miyoshi H, Tsutsumi T, Miyazawa T, Ishibashi K, Horie T, Imai K, Todoroki T, Kimura S, Koike K.

Cancer Res. 2001 Jun 1;61(11):4365-70.

13.

Protective role of amantadine in mitochondrial dysfunction and oxidative stress mediated by hepatitis C virus protein expression.

Quarato G, Scrima R, Ripoli M, Agriesti F, Moradpour D, Capitanio N, Piccoli C.

Biochem Pharmacol. 2014 Jun 15;89(4):545-56. doi: 10.1016/j.bcp.2014.03.018. Epub 2014 Apr 12.

PMID:
24726442
14.

Hepatitis C virus core protein stimulates hepatocyte growth: correlation with upregulation of wnt-1 expression.

Fukutomi T, Zhou Y, Kawai S, Eguchi H, Wands JR, Li J.

Hepatology. 2005 May;41(5):1096-105.

PMID:
15841445
15.

Mitochondrial electron transport inhibition in full genomic hepatitis C virus replicon cells is restored by reducing viral replication.

Ando M, Korenaga M, Hino K, Ikeda M, Kato N, Nishina S, Hidaka I, Sakaida I.

Liver Int. 2008 Sep;28(8):1158-66. doi: 10.1111/j.1478-3231.2008.01720.x. Epub 2008 Apr 11.

PMID:
18410284
16.

Tacrolimus ameliorates metabolic disturbance and oxidative stress caused by hepatitis C virus core protein: analysis using mouse model and cultured cells.

Moriya K, Miyoshi H, Tsutsumi T, Shinzawa S, Fujie H, Shintani Y, Yotsuyanagi H, Moriishi K, Matsuura Y, Suzuki T, Miyamura T, Koike K.

Am J Pathol. 2009 Oct;175(4):1515-24. doi: 10.2353/ajpath.2009.090102. Epub 2009 Sep 3.

17.

Mechanisms for inhibition of hepatitis B virus gene expression and replication by hepatitis C virus core protein.

Chen SY, Kao CF, Chen CM, Shih CM, Hsu MJ, Chao CH, Wang SH, You LR, Lee YH.

J Biol Chem. 2003 Jan 3;278(1):591-607. Epub 2002 Oct 24.

18.

Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins.

Shi ST, Polyak SJ, Tu H, Taylor DR, Gretch DR, Lai MM.

Virology. 2002 Jan 20;292(2):198-210.

19.

Proteomic profiling of cellular proteins interacting with the hepatitis C virus core protein.

Kang SM, Shin MJ, Kim JH, Oh JW.

Proteomics. 2005 May;5(8):2227-37.

PMID:
15846844
20.

Hepatitis C virus core protein compromises iron-induced activation of antioxidants in mice and HepG2 cells.

Moriya K, Miyoshi H, Shinzawa S, Tsutsumi T, Fujie H, Goto K, Shintani Y, Yotsuyanagi H, Koike K.

J Med Virol. 2010 May;82(5):776-92. doi: 10.1002/jmv.21661.

PMID:
20336713

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