Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 80

1.

Role of partitioning-defective 1/microtubule affinity-regulating kinases in the morphogenetic activity of Helicobacter pylori CagA.

Lu H, Murata-Kamiya N, Saito Y, Hatakeyama M.

J Biol Chem. 2009 Aug 21;284(34):23024-36. doi: 10.1074/jbc.M109.001008. Epub 2009 Jun 24.

2.

Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity.

Saadat I, Higashi H, Obuse C, Umeda M, Murata-Kamiya N, Saito Y, Lu H, Ohnishi N, Azuma T, Suzuki A, Ohno S, Hatakeyama M.

Nature. 2007 May 17;447(7142):330-3.

PMID:
17507984
3.

Structural and functional diversity in the PAR1b/MARK2-binding region of Helicobacter pylori CagA.

Lu HS, Saito Y, Umeda M, Murata-Kamiya N, Zhang HM, Higashi H, Hatakeyama M.

Cancer Sci. 2008 Oct;99(10):2004-11. doi: 10.1111/j.1349-7006.2008.00950.x.

4.

Potentiation of Helicobacter pylori CagA protein virulence through homodimerization.

Nagase L, Murata-Kamiya N, Hatakeyama M.

J Biol Chem. 2011 Sep 23;286(38):33622-31. doi: 10.1074/jbc.M111.258673. Epub 2011 Aug 3.

5.

Natural variant of the Helicobacter pylori CagA oncoprotein that lost the ability to interact with PAR1.

Hashi K, Murata-Kamiya N, Varon C, Mégraud F, Dominguez-Bello MG, Hatakeyama M.

Cancer Sci. 2014 Mar;105(3):245-51. doi: 10.1111/cas.12342. Epub 2014 Feb 12.

6.

Helicobacter pylori CagA induces Ras-independent morphogenetic response through SHP-2 recruitment and activation.

Higashi H, Nakaya A, Tsutsumi R, Yokoyama K, Fujii Y, Ishikawa S, Higuchi M, Takahashi A, Kurashima Y, Teishikata Y, Tanaka S, Azuma T, Hatakeyama M.

J Biol Chem. 2004 Apr 23;279(17):17205-16. Epub 2004 Feb 12.

7.

Helicobacter pylori CagA causes mitotic impairment and induces chromosomal instability.

Umeda M, Murata-Kamiya N, Saito Y, Ohba Y, Takahashi M, Hatakeyama M.

J Biol Chem. 2009 Aug 14;284(33):22166-72. doi: 10.1074/jbc.M109.035766. Epub 2009 Jun 22.

8.

Stability of Helicobacter pylori CagA oncoprotein in human gastric epithelial cells.

Ishikawa S, Ohta T, Hatakeyama M.

FEBS Lett. 2009 Jul 21;583(14):2414-8. doi: 10.1016/j.febslet.2009.06.043. Epub 2009 Jun 26.

9.

Focal adhesion kinase is a substrate and downstream effector of SHP-2 complexed with Helicobacter pylori CagA.

Tsutsumi R, Takahashi A, Azuma T, Higashi H, Hatakeyama M.

Mol Cell Biol. 2006 Jan;26(1):261-76.

10.

Structural basis and functional consequence of Helicobacter pylori CagA multimerization in cells.

Ren S, Higashi H, Lu H, Azuma T, Hatakeyama M.

J Biol Chem. 2006 Oct 27;281(43):32344-52. Epub 2006 Sep 5.

11.

Impact of structural polymorphism for the Helicobacter pylori CagA oncoprotein on binding to polarity-regulating kinase PAR1b.

Nishikawa H, Hayashi T, Arisaka F, Senda T, Hatakeyama M.

Sci Rep. 2016 Jul 22;6:30031. doi: 10.1038/srep30031.

12.

PAR1b takes the stage in the morphogenetic and motogenetic activity of Helicobacter pylori CagA oncoprotein.

Yamahashi Y, Hatakeyama M.

Cell Adh Migr. 2013 Jan-Feb;7(1):11-8. doi: 10.4161/cam.21936. Epub 2012 Oct 17.

13.

Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse.

Ohnishi N, Yuasa H, Tanaka S, Sawa H, Miura M, Matsui A, Higashi H, Musashi M, Iwabuchi K, Suzuki M, Yamada G, Azuma T, Hatakeyama M.

Proc Natl Acad Sci U S A. 2008 Jan 22;105(3):1003-8. doi: 10.1073/pnas.0711183105. Epub 2008 Jan 11.

14.

[Oncogenic mechanism of Helicobacter pylori].

Hatakeyama M.

Nihon Rinsho Meneki Gakkai Kaishi. 2008 Jun;31(3):132-40. Japanese.

15.

Attenuation of Helicobacter pylori CagA x SHP-2 signaling by interaction between CagA and C-terminal Src kinase.

Tsutsumi R, Higashi H, Higuchi M, Okada M, Hatakeyama M.

J Biol Chem. 2003 Feb 7;278(6):3664-70. Epub 2002 Nov 21.

16.

Influence of EPIYA-repeat polymorphism on the phosphorylation-dependent biological activity of Helicobacter pylori CagA.

Naito M, Yamazaki T, Tsutsumi R, Higashi H, Onoe K, Yamazaki S, Azuma T, Hatakeyama M.

Gastroenterology. 2006 Apr;130(4):1181-90.

PMID:
16618412
17.

Polarity-regulating kinase partitioning-defective 1b (PAR1b) phosphorylates guanine nucleotide exchange factor H1 (GEF-H1) to regulate RhoA-dependent actin cytoskeletal reorganization.

Yamahashi Y, Saito Y, Murata-Kamiya N, Hatakeyama M.

J Biol Chem. 2011 Dec 30;286(52):44576-84. doi: 10.1074/jbc.M111.267021. Epub 2011 Nov 9.

18.

Linking epithelial polarity and carcinogenesis by multitasking Helicobacter pylori virulence factor CagA.

Hatakeyama M.

Oncogene. 2008 Nov 24;27(55):7047-54. doi: 10.1038/onc.2008.353. Review.

PMID:
19029944
19.
20.

Conversion of Helicobacter pylori CagA from senescence inducer to oncogenic driver through polarity-dependent regulation of p21.

Saito Y, Murata-Kamiya N, Hirayama T, Ohba Y, Hatakeyama M.

J Exp Med. 2010 Sep 27;207(10):2157-74. doi: 10.1084/jem.20100602. Epub 2010 Sep 20.

Supplemental Content

Support Center