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Genome-wide screening of human T-cell epitopes in influenza A virus reveals a broad spectrum of CD4(+) T-cell responses to internal proteins, hemagglutinins, and neuraminidases.

Babon JA, Cruz J, Orphin L, Pazoles P, Co MD, Ennis FA, Terajima M.

Hum Immunol. 2009 Sep;70(9):711-21. doi: 10.1016/j.humimm.2009.06.004. Epub 2009 Jun 11.


Identification of HLA class II H5N1 hemagglutinin epitopes following subvirion influenza A (H5N1) vaccination.

Zinckgraf JW, Sposato M, Zielinski V, Powell D, Treanor JJ, von Hofe E.

Vaccine. 2009 Aug 27;27(39):5393-401. doi: 10.1016/j.vaccine.2009.06.081. Epub 2009 Jul 9.


Universal H1N1 influenza vaccine development: identification of consensus class II hemagglutinin and neuraminidase epitopes derived from strains circulating between 1980 and 2011.

Moise L, Terry F, Ardito M, Tassone R, Latimer H, Boyle C, Martin WD, De Groot AS.

Hum Vaccin Immunother. 2013 Jul;9(7):1598-607. doi: 10.4161/hv.25598. Epub 2013 Jul 11.


Healthy human subjects have CD4+ T cells directed against H5N1 influenza virus.

Roti M, Yang J, Berger D, Huston L, James EA, Kwok WW.

J Immunol. 2008 Feb 1;180(3):1758-68.


A human CD4+ T cell epitope in the influenza hemagglutinin is cross-reactive to influenza A virus subtypes and to influenza B virus.

Babon JA, Cruz J, Ennis FA, Yin L, Terajima M.

J Virol. 2012 Sep;86(17):9233-43. doi: 10.1128/JVI.06325-11. Epub 2012 Jun 20. Erratum in: J Virol. 2013 Aug;87(16):9396.


Human cytotoxic T-lymphocyte repertoire to influenza A viruses.

Jameson J, Cruz J, Ennis FA.

J Virol. 1998 Nov;72(11):8682-9.


In vitro responses to avian influenza H5 by human CD4 T cells.

Cusick MF, Wang S, Eckels DD.

J Immunol. 2009 Nov 15;183(10):6432-41. doi: 10.4049/jimmunol.0901617. Epub 2009 Oct 19.


Identification of a dual-specific T cell epitope of the hemagglutinin antigen of an h5 avian influenza virus in chickens.

Haghighi HR, Read LR, Haeryfar SM, Behboudi S, Sharif S.

PLoS One. 2009 Nov 10;4(11):e7772. doi: 10.1371/journal.pone.0007772.


Identification of novel consensus CD4 T-cell epitopes from clade B HIV-1 whole genome that are frequently recognized by HIV-1 infected patients.

Fonseca SG, Coutinho-Silva A, Fonseca LA, Segurado AC, Moraes SL, Rodrigues H, Hammer J, Kallás EG, Sidney J, Sette A, Kalil J, Cunha-Neto E.

AIDS. 2006 Nov 28;20(18):2263-73.


Multiplex mapping of CD4 T cell epitopes using class II tetramers.

Yang J, James EA, Huston L, Danke NA, Liu AW, Kwok WW.

Clin Immunol. 2006 Jul;120(1):21-32. Epub 2006 May 4.


Specificity of T cells in synovial fluid: high frequencies of CD8(+) T cells that are specific for certain viral epitopes.

Tan LC, Mowat AG, Fazou C, Rostron T, Roskell H, Dunbar PR, Tournay C, Romagné F, Peyrat MA, Houssaint E, Bonneville M, Rickinson AB, McMichael AJ, Callan MF.

Arthritis Res. 2000;2(2):154-64. Epub 2000 Feb 7.


Conserved peptides containing overlapping CD4+ and CD8+ T-cell epitopes in the H1N1 influenza virus: an immunoinformatics approach.

Lohia N, Baranwal M.

Viral Immunol. 2014 Jun;27(5):225-34. doi: 10.1089/vim.2013.0135. Epub 2014 May 12.


Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individuals.

Lee LY, Ha do LA, Simmons C, de Jong MD, Chau NV, Schumacher R, Peng YC, McMichael AJ, Farrar JJ, Smith GL, Townsend AR, Askonas BA, Rowland-Jones S, Dong T.

J Clin Invest. 2008 Oct;118(10):3478-90. doi: 10.1172/JCI32460. Erratum in: J Clin Invest. 2012 Nov 1;122(11):4301.


Rapid detection of H5N1 subtype influenza viruses by antigen capture enzyme-linked immunosorbent assay using H5- and N1-specific monoclonal antibodies.

Ho HT, Qian HL, He F, Meng T, Szyporta M, Prabhu N, Prabakaran M, Chan KP, Kwang J.

Clin Vaccine Immunol. 2009 May;16(5):726-32. doi: 10.1128/CVI.00465-08. Epub 2009 Mar 25.


Differential capacity of T cell priming in naive donors of promiscuous CD4+ T cell epitopes of HCV NS3 and Core proteins.

Castelli FA, Leleu M, Pouvelle-Moratille S, Farci S, Zarour HM, Andrieu M, Auriault C, Ménez A, Georges B, Maillere B.

Eur J Immunol. 2007 Jun;37(6):1513-23.


Human CD4+ T-cell repertoire of responses to influenza A virus hemagglutinin after recent natural infection.

Gelder CM, Welsh KI, Faith A, Lamb JR, Askonas BA.

J Virol. 1995 Dec;69(12):7497-506.


Identifying conserved DR1501-restricted CD4(+) T-cell epitopes in avian H5N1 hemagglutinin proteins.

Wang SF, Yao L, Liu SJ, Chong P, Liu WT, Chen YM, Huang JC.

Viral Immunol. 2010 Dec;23(6):585-93. doi: 10.1089/vim.2010.0058.


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