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Items: 1 to 20 of 108

1.

Suppression of hepatitis C virus replication by protein kinase C-related kinase 2 inhibitors that block phosphorylation of viral RNA polymerase.

Kim SJ, Kim JH, Sun JM, Kim MG, Oh JW.

J Viral Hepat. 2009 Oct;16(10):697-704. doi: 10.1111/j.1365-2893.2009.01108.x. Epub 2009 Feb 23.

PMID:
19243496
2.

Destabilization of PDK1 by Hsp90 inactivation suppresses hepatitis C virus replication through inhibition of PRK2-mediated viral RNA polymerase phosphorylation.

Kim MG, Moon JS, Kim EJ, Lee SH, Oh JW.

Biochem Biophys Res Commun. 2012 Apr 27;421(1):112-8. doi: 10.1016/j.bbrc.2012.03.126. Epub 2012 Apr 3.

PMID:
22490666
3.

Phosphorylation of hepatitis C virus RNA polymerases ser29 and ser42 by protein kinase C-related kinase 2 regulates viral RNA replication.

Han SH, Kim SJ, Kim EJ, Kim TE, Moon JS, Kim GW, Lee SH, Cho K, Yoo JS, Son WS, Rhee JK, Han SH, Oh JW.

J Virol. 2014 Oct;88(19):11240-52. doi: 10.1128/JVI.01826-14. Epub 2014 Jul 16.

4.

Alpha interferon induces distinct translational control programs to suppress hepatitis C virus RNA replication.

Wang C, Pflugheber J, Sumpter R Jr, Sodora DL, Hui D, Sen GC, Gale M Jr.

J Virol. 2003 Apr;77(7):3898-912.

5.

Galactosylated Lipidoid Nanoparticles for Delivery of Small Interfering RNA to Inhibit Hepatitis C Viral Replication In Vivo.

Park HJ, Jeon EJ, Lee JS, Hong SH, Cho AN, Lee J, Moon JS, Jung KE, Oh JW, Lee H, Cho SW.

Adv Healthc Mater. 2016 Nov;5(22):2931-2941. doi: 10.1002/adhm.201600416. Epub 2016 Oct 24.

PMID:
27774775
6.

Double-stranded RNA-activated protein kinase inhibits hepatitis C virus replication but may be not essential in interferon treatment.

Chang JH, Kato N, Muroyama R, Taniguchi H, Guleng B, Dharel N, Shao RX, Tateishi K, Jazag A, Kawabe T, Omata M.

Liver Int. 2010 Feb;30(2):311-8. doi: 10.1111/j.1478-3231.2009.02144.x. Epub 2009 Oct 16.

PMID:
19840259
7.

Inhibition of hepatitis C virus replication by Monascus pigment derivatives that interfere with viral RNA polymerase activity and the mevalonate biosynthesis pathway.

Sun JM, Kim SJ, Kim GW, Rhee JK, Kim ND, Jung H, Jeun J, Lee SH, Han SH, Shin CS, Oh JW.

J Antimicrob Chemother. 2012 Jan;67(1):49-58. doi: 10.1093/jac/dkr432. Epub 2011 Nov 9.

PMID:
22076990
8.

Hepatitis C virus replication is inhibited by 22beta-methoxyolean-12-ene-3beta, 24(4beta)-diol (ME3738) through enhancing interferon-beta.

Hiasa Y, Kuzuhara H, Tokumoto Y, Konishi I, Yamashita N, Matsuura B, Michitaka K, Chung RT, Onji M.

Hepatology. 2008 Jul;48(1):59-69. doi: 10.1002/hep.22289.

PMID:
18459156
9.

Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells.

Plumlee CR, Lazaro CA, Fausto N, Polyak SJ.

Virol J. 2005 Dec 2;2:89.

10.

Protein kinase C-related kinase 2 regulates hepatitis C virus RNA polymerase function by phosphorylation.

Kim SJ, Kim JH, Kim YG, Lim HS, Oh JW.

J Biol Chem. 2004 Nov 26;279(48):50031-41. Epub 2004 Sep 13.

11.

Anti-ulcer agent teprenone inhibits hepatitis C virus replication: potential treatment for hepatitis C.

Ikeda M, Kawai Y, Mori K, Yano M, Abe K, Nishimura G, Dansako H, Ariumi Y, Wakita T, Yamamoto K, Kato N.

Liver Int. 2011 Jul;31(6):871-80. doi: 10.1111/j.1478-3231.2011.02499.x. Epub 2011 Mar 13.

PMID:
21645219
12.

Identification of three interferon-inducible cellular enzymes that inhibit the replication of hepatitis C virus.

Jiang D, Guo H, Xu C, Chang J, Gu B, Wang L, Block TM, Guo JT.

J Virol. 2008 Feb;82(4):1665-78. Epub 2007 Dec 12.

13.

Discovery and characterization of substituted diphenyl heterocyclic compounds as potent and selective inhibitors of hepatitis C virus replication.

Huang P, Goff DA, Huang Q, Martinez A, Xu X, Crowder S, Issakani SD, Anderson E, Sheng N, Achacoso P, Yen A, Kinsella T, Darwish IS, Kolluri R, Hong H, Qu K, Stauffer E, Goldstein E, Singh R, Payan DG, Lu HH.

Antimicrob Agents Chemother. 2008 Apr;52(4):1419-29. doi: 10.1128/AAC.00525-07. Epub 2008 Jan 28.

14.

Inhibition of hepatitis C virus RNA replication by short hairpin RNA synthesized by T7 RNA polymerase in hepatitis C virus subgenomic replicons.

Hamazaki H, Ujino S, Miyano-Kurosaki N, Shimotohno K, Takaku H.

Biochem Biophys Res Commun. 2006 May 12;343(3):988-94. Epub 2006 Mar 29.

PMID:
16566896
15.

ME3738 enhances the effect of interferon and inhibits hepatitis C virus replication both in vitro and in vivo.

Abe H, Imamura M, Hiraga N, Tsuge M, Mitsui F, Kawaoka T, Takahashi S, Ochi H, Maekawa T, Hayes CN, Tateno C, Yoshizato K, Murakami S, Yamashita N, Matsuhira T, Asai K, Chayama K.

J Hepatol. 2011 Jul;55(1):11-8. doi: 10.1016/j.jhep.2010.10.017. Epub 2010 Nov 29.

PMID:
21145867
16.

Conventional protein kinase C inhibition prevents alpha interferon-mediated hepatitis C virus replicon clearance by impairing STAT activation.

Fimia GM, Evangelisti C, Alonzi T, Romani M, Fratini F, Paonessa G, Ippolito G, Tripodi M, Piacentini M.

J Virol. 2004 Dec;78(23):12809-16.

17.

Effect of alpha interferon on the hepatitis C virus replicon.

Guo JT, Bichko VV, Seeger C.

J Virol. 2001 Sep;75(18):8516-23.

18.

Novel nonnucleoside inhibitor of hepatitis C virus RNA-dependent RNA polymerase.

Howe AY, Bloom J, Baldick CJ, Benetatos CA, Cheng H, Christensen JS, Chunduru SK, Coburn GA, Feld B, Gopalsamy A, Gorczyca WP, Herrmann S, Johann S, Jiang X, Kimberland ML, Krisnamurthy G, Olson M, Orlowski M, Swanberg S, Thompson I, Thorn M, Del Vecchio A, Young DC, van Zeijl M, Ellingboe JW, Upeslacis J, Collett M, Mansour TS, O'Connell JF.

Antimicrob Agents Chemother. 2004 Dec;48(12):4813-21.

19.

Replication studies using genotype 1a subgenomic hepatitis C virus replicons.

Gu B, Gates AT, Isken O, Behrens SE, Sarisky RT.

J Virol. 2003 May;77(9):5352-9.

20.

In vitro activity and resistance profile of samatasvir, a novel NS5A replication inhibitor of hepatitis C virus.

Bilello JP, Lallos LB, McCarville JF, La Colla M, Serra I, Chapron C, Gillum JM, Pierra C, Standring DN, Seifer M.

Antimicrob Agents Chemother. 2014 Aug;58(8):4431-42. doi: 10.1128/AAC.02777-13. Epub 2014 May 27.

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