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CLEC5A-Mediated Enhancement of the Inflammatory Response in Myeloid Cells Contributes to Influenza Virus Pathogenicity In Vivo.

Teng O, Chen ST, Hsu TL, Sia SF, Cole S, Valkenburg SA, Hsu TY, Zheng JT, Tu W, Bruzzone R, Peiris JSM, Hsieh SL, Yen HL.

J Virol. 2016 Dec 16;91(1). pii: e01813-16. doi: 10.1128/JVI.01813-16. Print 2017 Jan 1.


Endogenous 4-1BB ligand plays a critical role in protection from influenza-induced disease.

Lin GH, Sedgmen BJ, Moraes TJ, Snell LM, Topham DJ, Watts TH.

J Immunol. 2009 Jan 15;182(2):934-47.


Inhibition of lectin-mediated innate host defences in vivo modulates disease severity during influenza virus infection.

Tate MD, Brooks AG, Reading PC.

Immunol Cell Biol. 2011 Mar;89(3):482-91. doi: 10.1038/icb.2010.113. Epub 2010 Oct 12.


Critical role of airway macrophages in modulating disease severity during influenza virus infection of mice.

Tate MD, Pickett DL, van Rooijen N, Brooks AG, Reading PC.

J Virol. 2010 Aug;84(15):7569-80. doi: 10.1128/JVI.00291-10. Epub 2010 May 26.


Impaired immune responses in the lungs of aged mice following influenza infection.

Toapanta FR, Ross TM.

Respir Res. 2009 Nov 18;10:112. doi: 10.1186/1465-9921-10-112.


The extracellular matrix protein mindin is a pattern-recognition molecule for microbial pathogens.

He YW, Li H, Zhang J, Hsu CL, Lin E, Zhang N, Guo J, Forbush KA, Bevan MJ.

Nat Immunol. 2004 Jan;5(1):88-97. Epub 2003 Dec 14.


The critical role of Notch ligand Delta-like 1 in the pathogenesis of influenza A virus (H1N1) infection.

Ito T, Allen RM, Carson WF 4th, Schaller M, Cavassani KA, Hogaboam CM, Lukacs NW, Matsukawa A, Kunkel SL.

PLoS Pathog. 2011 Nov;7(11):e1002341. doi: 10.1371/journal.ppat.1002341. Epub 2011 Nov 3.


Lowering the threshold of lung innate immune cell activation alters susceptibility to secondary bacterial superinfection.

Goulding J, Godlee A, Vekaria S, Hilty M, Snelgrove R, Hussell T.

J Infect Dis. 2011 Oct 1;204(7):1086-94. doi: 10.1093/infdis/jir467.


Impaired clearance of influenza A virus in obese, leptin receptor deficient mice is independent of leptin signaling in the lung epithelium and macrophages.

Radigan KA, Morales-Nebreda L, Soberanes S, Nicholson T, Nigdelioglu R, Cho T, Chi M, Hamanaka RB, Misharin AV, Perlman H, Budinger GR, Mutlu GM.

PLoS One. 2014 Sep 18;9(9):e108138. doi: 10.1371/journal.pone.0108138. eCollection 2014.


Activation of invariant NKT cells enhances the innate immune response and improves the disease course in influenza A virus infection.

Ho LP, Denney L, Luhn K, Teoh D, Clelland C, McMichael AJ.

Eur J Immunol. 2008 Jul;38(7):1913-22. doi: 10.1002/eji.200738017.


An H1-H3 chimeric influenza virosome confers complete protection against lethal challenge with PR8 (H1N1) and X47 (H3N2) viruses in mice.

Abdoli A, Soleimanjahi H, Tavassoti Kheiri M, Jamali A, Mazaheri V, Abdollahpour Alitappeh M.

Pathog Dis. 2014 Dec;72(3):197-207. doi: 10.1111/2049-632X.12206. Epub 2014 Sep 1.


Caspase-1 deficient mice are more susceptible to influenza A virus infection with PA variation.

Huang CH, Chen CJ, Yen CT, Yu CP, Huang PN, Kuo RL, Lin SJ, Chang CK, Shih SR.

J Infect Dis. 2013 Dec 1;208(11):1898-905. doi: 10.1093/infdis/jit381. Epub 2013 Jul 30.


A role for IL-15 in the migration of effector CD8 T cells to the lung airways following influenza infection.

Verbist KC, Cole CJ, Field MB, Klonowski KD.

J Immunol. 2011 Jan 1;186(1):174-82. doi: 10.4049/jimmunol.1002613. Epub 2010 Nov 22.


The magnitude of the T cell response to a clinically significant dose of influenza virus is regulated by TRAIL.

Brincks EL, Gurung P, Langlois RA, Hemann EA, Legge KL, Griffith TS.

J Immunol. 2011 Nov 1;187(9):4581-8. doi: 10.4049/jimmunol.1002241. Epub 2011 Sep 21.


Antiviral activity of the long chain pentraxin PTX3 against influenza viruses.

Reading PC, Bozza S, Gilbertson B, Tate M, Moretti S, Job ER, Crouch EC, Brooks AG, Brown LE, Bottazzi B, Romani L, Mantovani A.

J Immunol. 2008 Mar 1;180(5):3391-8.


Induction of heterosubtypic immunity to influenza virus by intranasal immunization.

Quan FS, Compans RW, Nguyen HH, Kang SM.

J Virol. 2008 Feb;82(3):1350-9. Epub 2007 Nov 21.


Immunization with influenza A NP-expressing vaccinia virus recombinant protects mice against experimental infection with human and avian influenza viruses.

Altstein AD, Gitelman AK, Smirnov YA, Piskareva LM, Zakharova LG, Pashvykina GV, Shmarov MM, Zhirnov OP, Varich NP, Ilyinskii PO, Shneider AM.

Arch Virol. 2006 May;151(5):921-31. Epub 2005 Nov 15.


Highly pathogenic avian influenza A H5N1 and pandemic H1N1 virus infections have different phenotypes in Toll-like receptor 3 knockout mice.

Leung YH, Nicholls JM, Ho CK, Sia SF, Mok CK, Valkenburg SA, Cheung P, Hui KP, Chan RW, Guan Y, Akira S, Peiris JS.

J Gen Virol. 2014 Sep;95(Pt 9):1870-9. doi: 10.1099/vir.0.066258-0. Epub 2014 May 30.

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