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Items: 1 to 20 of 401

1.

Avian and 1918 Spanish influenza a virus NS1 proteins bind to Crk/CrkL Src homology 3 domains to activate host cell signaling.

Heikkinen LS, Kazlauskas A, Melén K, Wagner R, Ziegler T, Julkunen I, Saksela K.

J Biol Chem. 2008 Feb 29;283(9):5719-27. doi: 10.1074/jbc.M707195200. Epub 2007 Dec 28.

2.

CRK adaptor protein expression is required for efficient replication of avian influenza A viruses and controls JNK-mediated apoptotic responses.

Hrincius ER, Wixler V, Wolff T, Wagner R, Ludwig S, Ehrhardt C.

Cell Microbiol. 2010 Jun;12(6):831-43. doi: 10.1111/j.1462-5822.2010.01436.x. Epub 2010 Jan 29.

PMID:
20088952
3.

NS1-binding protein abrogates the elevation of cell viability by the influenza A virus NS1 protein in association with CRKL.

Miyazaki M, Nishihara H, Hasegawa H, Tashiro M, Wang L, Kimura T, Tanino M, Tsuda M, Tanaka S.

Biochem Biophys Res Commun. 2013 Nov 29;441(4):953-7. doi: 10.1016/j.bbrc.2013.11.011. Epub 2013 Nov 9.

PMID:
24220336
5.

The germinal center kinase (GCK)-related protein kinases HPK1 and KHS are candidates for highly selective signal transducers of Crk family adapter proteins.

Oehrl W, Kardinal C, Ruf S, Adermann K, Groffen J, Feng GS, Blenis J, Tan TH, Feller SM.

Oncogene. 1998 Oct 15;17(15):1893-901.

6.

Heterologous SH3-p85beta inhibits influenza A virus replication.

Zhang DG, Li WZ, Wang GF, Su Y, Zeng J, Zhang C, Zeng XX, Chen XX, Xu YX, Li KS.

Virol J. 2010 Jul 23;7:170. doi: 10.1186/1743-422X-7-170.

7.

Mechanism of influenza A virus NS1 protein interaction with the p85beta, but not the p85alpha, subunit of phosphatidylinositol 3-kinase (PI3K) and up-regulation of PI3K activity.

Li Y, Anderson DH, Liu Q, Zhou Y.

J Biol Chem. 2008 Aug 22;283(34):23397-409. doi: 10.1074/jbc.M802737200. Epub 2008 Jun 5.

8.

Development of highly selective SH3 binding peptides for Crk and CRKL which disrupt Crk-complexes with DOCK180, SoS and C3G.

Posern G, Zheng J, Knudsen BS, Kardinal C, Müller KB, Voss J, Shishido T, Cowburn D, Cheng G, Wang B, Kruh GD, Burrell SK, Jacobson CA, Lenz DM, Zamborelli TJ, Adermann K, Hanafusa H, Feller SM.

Oncogene. 1998 Apr 16;16(15):1903-12.

9.

Nuclear Translocation of Crk Adaptor Proteins by the Influenza A Virus NS1 Protein.

Ylösmäki L, Fagerlund R, Kuisma I, Julkunen I, Saksela K.

Viruses. 2016 Apr 15;8(4):101. doi: 10.3390/v8040101.

10.
11.

Reorganization of the host cell Crk(L)-PI3 kinase signaling complex by the influenza A virus NS1 protein.

Ylösmäki L, Schmotz C, Ylösmäki E, Saksela K.

Virology. 2015 Oct;484:146-52. doi: 10.1016/j.virol.2015.06.009. Epub 2015 Jun 19.

12.
13.

Virulence determinants of avian H5N1 influenza A virus in mammalian and avian hosts: role of the C-terminal ESEV motif in the viral NS1 protein.

Zielecki F, Semmler I, Kalthoff D, Voss D, Mauel S, Gruber AD, Beer M, Wolff T.

J Virol. 2010 Oct;84(20):10708-18. doi: 10.1128/JVI.00610-10. Epub 2010 Aug 4.

14.

Characterization of the interaction of influenza virus NS1 with Akt.

Matsuda M, Suizu F, Hirata N, Miyazaki T, Obuse C, Noguchi M.

Biochem Biophys Res Commun. 2010 May 7;395(3):312-7. doi: 10.1016/j.bbrc.2010.03.166. Epub 2010 Apr 1.

PMID:
20362551
15.

Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2.

Sparks AB, Rider JE, Hoffman NG, Fowlkes DM, Quillam LA, Kay BK.

Proc Natl Acad Sci U S A. 1996 Feb 20;93(4):1540-4.

16.

SH3 binding motif 1 in influenza A virus NS1 protein is essential for PI3K/Akt signaling pathway activation.

Shin YK, Li Y, Liu Q, Anderson DH, Babiuk LA, Zhou Y.

J Virol. 2007 Dec;81(23):12730-9. Epub 2007 Sep 19.

17.

Enhancement of guanine-nucleotide exchange activity of C3G for Rap1 by the expression of Crk, CrkL, and Grb2.

Ichiba T, Kuraishi Y, Sakai O, Nagata S, Groffen J, Kurata T, Hattori S, Matsuda M.

J Biol Chem. 1997 Aug 29;272(35):22215-20.

18.

Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus.

Hale BG, Steel J, Manicassamy B, Medina RA, Ye J, Hickman D, Lowen AC, Perez DR, García-Sastre A.

J Gen Virol. 2010 Jul;91(Pt 7):1737-42. doi: 10.1099/vir.0.020925-0. Epub 2010 Mar 17.

19.

Inhibition of host innate immune responses and pathogenicity of recombinant Newcastle disease viruses expressing NS1 genes of influenza A viruses.

Kim SH, Samal SK.

J Gen Virol. 2010 Aug;91(Pt 8):1996-2001. doi: 10.1099/vir.0.021766-0. Epub 2010 Apr 21.

PMID:
20410312
20.

CrkL activates integrin-mediated hematopoietic cell adhesion through the guanine nucleotide exchange factor C3G.

Arai A, Nosaka Y, Kohsaka H, Miyasaka N, Miura O.

Blood. 1999 Jun 1;93(11):3713-22.

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