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Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus.

Ahn J, Chung KS, Kim DU, Won M, Kim L, Kim KS, Nam M, Choi SJ, Kim HC, Yoon M, Chae SK, Hoe KL.

J Biochem Mol Biol. 2004 Nov 30;37(6):741-8.


Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins.

Shi ST, Polyak SJ, Tu H, Taylor DR, Gretch DR, Lai MM.

Virology. 2002 Jan 20;292(2):198-210.


The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade.

Street A, Macdonald A, Crowder K, Harris M.

J Biol Chem. 2004 Mar 26;279(13):12232-41. Epub 2004 Jan 5.


Cleavage of hepatitis C virus nonstructural protein 5A by a caspase-like protease(s) in mammalian cells.

Satoh S, Hirota M, Noguchi T, Hijikata M, Handa H, Shimotohno K.

Virology. 2000 May 10;270(2):476-87.


Human VAP-B is involved in hepatitis C virus replication through interaction with NS5A and NS5B.

Hamamoto I, Nishimura Y, Okamoto T, Aizaki H, Liu M, Mori Y, Abe T, Suzuki T, Lai MM, Miyamura T, Moriishi K, Matsuura Y.

J Virol. 2005 Nov;79(21):13473-82.


Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein.

Tu H, Gao L, Shi ST, Taylor DR, Yang T, Mircheff AK, Wen Y, Gorbalenya AE, Hwang SB, Lai MM.

Virology. 1999 Oct 10;263(1):30-41.


Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly.

Appel N, Zayas M, Miller S, Krijnse-Locker J, Schaller T, Friebe P, Kallis S, Engel U, Bartenschlager R.

PLoS Pathog. 2008 Mar 28;4(3):e1000035. doi: 10.1371/journal.ppat.1000035.


Bovine viral diarrhea virus non-structural protein 5A interacts with NIK- and IKKbeta-binding protein.

Zahoor MA, Yamane D, Mohamed YM, Suda Y, Kobayashi K, Kato K, Tohya Y, Akashi H.

J Gen Virol. 2010 Aug;91(Pt 8):1939-48. doi: 10.1099/vir.0.020990-0. Epub 2010 May 5.


Hepatitis C virus NS5A protein is phosphorylated by casein kinase II.

Kim J, Lee D, Choe J.

Biochem Biophys Res Commun. 1999 Apr 21;257(3):777-81.


The NS5A protein of hepatitis C virus is a zinc metalloprotein.

Tellinghuisen TL, Marcotrigiano J, Gorbalenya AE, Rice CM.

J Biol Chem. 2004 Nov 19;279(47):48576-87. Epub 2004 Aug 31.


Hepatitis C virus non-structural protein NS5A interacts with FKBP38 and inhibits apoptosis in Huh7 hepatoma cells.

Wang J, Tong W, Zhang X, Chen L, Yi Z, Pan T, Hu Y, Xiang L, Yuan Z.

FEBS Lett. 2006 Aug 7;580(18):4392-400. Epub 2006 Jul 17.


Modulation of interferon expression by hepatitis C virus NS5A protein and human homeodomain protein PTX1.

Ghosh AK, Majumder M, Steele R, Ray R, Ray RB.

Virology. 2003 Feb 1;306(1):51-9.


Domain 2 of nonstructural protein 5A (NS5A) of hepatitis C virus is natively unfolded.

Liang Y, Ye H, Kang CB, Yoon HS.

Biochemistry. 2007 Oct 16;46(41):11550-8. Epub 2007 Sep 19.


Hepatitis C virus nonstructural protein 5A (NS5A) is an RNA-binding protein.

Huang L, Hwang J, Sharma SD, Hargittai MR, Chen Y, Arnold JJ, Raney KD, Cameron CE.

J Biol Chem. 2005 Oct 28;280(43):36417-28. Epub 2005 Aug 25.


Phosphorylation of hepatitis C virus NS5A nonstructural protein: a new paradigm for phosphorylation-dependent viral RNA replication?

Huang Y, Staschke K, De Francesco R, Tan SL.

Virology. 2007 Jul 20;364(1):1-9. Epub 2007 Apr 2. Review.


Characterization of a HCV NS5A protein derived from a patient with hepatoma.

Yeh CT, Chang MH, Shyu WC, Chang ML, Yang PY, Tsao ML, Lai HY.

Biochem Biophys Res Commun. 2005 Feb 11;327(2):516-22.


Natural genetic engineering of hepatitis C virus NS5A for immune system counterattack.

El Hefnawi MM, El Behaidy WH, Youssif AA, Ghalwash AZ, El Housseiny LA, Zada S.

Ann N Y Acad Sci. 2009 Oct;1178:173-85. doi: 10.1111/j.1749-6632.2009.05003.x.


NS5ATP9, a gene up-regulated by HCV NS5A protein.

Shi L, Zhang SL, Li K, Hong Y, Wang Q, Li Y, Guo J, Fan WH, Zhang L, Cheng J.

Cancer Lett. 2008 Feb 8;259(2):192-7.


Association of amino acid variations in the NS5A and E2-PePHD region of hepatitis C virus 1b with hepatocellular carcinoma.

Hung CH, Chen CH, Lee CM, Wu CM, Hu TH, Wang JH, Yen YH, Lu SN.

J Viral Hepat. 2008 Jan;15(1):58-65.


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