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Items: 1 to 20 of 146

1.

Brain inflammation and Alzheimer's-like pathology in individuals exposed to severe air pollution.

Calderón-Garcidueñas L, Reed W, Maronpot RR, Henríquez-Roldán C, Delgado-Chavez R, Calderón-Garcidueñas A, Dragustinovis I, Franco-Lira M, Aragón-Flores M, Solt AC, Altenburg M, Torres-Jardón R, Swenberg JA.

Toxicol Pathol. 2004 Nov-Dec;32(6):650-8.

PMID:
15513908
2.

Pediatric respiratory and systemic effects of chronic air pollution exposure: nose, lung, heart, and brain pathology.

Calderón-Garcidueñas L, Franco-Lira M, Torres-Jardón R, Henriquez-Roldán C, Barragán-Mejía G, Valencia-Salazar G, González-Maciel A, Reynoso-Robles R, Villarreal-Calderón R, Reed W.

Toxicol Pathol. 2007 Jan;35(1):154-62. Review.

PMID:
17325984
3.

Long-term air pollution exposure is associated with neuroinflammation, an altered innate immune response, disruption of the blood-brain barrier, ultrafine particulate deposition, and accumulation of amyloid beta-42 and alpha-synuclein in children and young adults.

Calderón-Garcidueñas L, Solt AC, Henríquez-Roldán C, Torres-Jardón R, Nuse B, Herritt L, Villarreal-Calderón R, Osnaya N, Stone I, García R, Brooks DM, González-Maciel A, Reynoso-Robles R, Delgado-Chávez R, Reed W.

Toxicol Pathol. 2008 Feb;36(2):289-310. doi: 10.1177/0192623307313011. Epub 2008 Mar 18.

PMID:
18349428
4.

DNA damage in nasal and brain tissues of canines exposed to air pollutants is associated with evidence of chronic brain inflammation and neurodegeneration.

Calderón-Garcidueñas L, Maronpot RR, Torres-Jardon R, Henríquez-Roldán C, Schoonhoven R, Acuña-Ayala H, Villarreal-Calderón A, Nakamura J, Fernando R, Reed W, Azzarelli B, Swenberg JA.

Toxicol Pathol. 2003 Sep-Oct;31(5):524-38.

PMID:
14692621
5.

Cyclooxygenase-2-positive macrophages infiltrate the Alzheimer's disease brain and damage the blood-brain barrier.

Fiala M, Liu QN, Sayre J, Pop V, Brahmandam V, Graves MC, Vinters HV.

Eur J Clin Invest. 2002 May;32(5):360-71.

PMID:
12027877
6.

Effects of a cyclooxygenase-2 preferential inhibitor in young healthy dogs exposed to air pollution: a pilot study.

Calderón-Garcidueñas L, Mora-Tiscareño A, Gómez-Garza G, Carrasco-Portugal Mdel C, Pérez-Guillé B, Flores-Murrieta FJ, Pérez-Guillé G, Osnaya N, Juárez-Olguín H, Monroy ME, Monroy S, González-Maciel A, Reynoso-Robles R, Villarreal-Calderon R, Patel SA, Kumarathasan P, Vincent R, Henríquez-Roldán C, Torres-Jardón R, Maronpot RR.

Toxicol Pathol. 2009 Aug;37(5):644-60. doi: 10.1177/0192623309340277.

PMID:
19638440
7.

mTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's disease.

Lafay-Chebassier C, Paccalin M, Page G, Barc-Pain S, Perault-Pochat MC, Gil R, Pradier L, Hugon J.

J Neurochem. 2005 Jul;94(1):215-25.

8.

Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice.

Heneka MT, Sastre M, Dumitrescu-Ozimek L, Hanke A, Dewachter I, Kuiperi C, O'Banion K, Klockgether T, Van Leuven F, Landreth GE.

Brain. 2005 Jun;128(Pt 6):1442-53. Epub 2005 Apr 7.

PMID:
15817521
9.

Relationship of neurofibrillary pathology to cerebral amyloid angiopathy in Alzheimer's disease.

Williams S, Chalmers K, Wilcock GK, Love S.

Neuropathol Appl Neurobiol. 2005 Aug;31(4):414-21.

PMID:
16008825
10.

Cyclooxygenase-2 in the hippocampus is up-regulated in Alzheimer's disease but not in variant Alzheimer's disease with cotton wool plaques in humans.

Yokota O, Terada S, Ishizu H, Ishihara T, Ujike H, Nakashima H, Nakashima Y, Kugo A, Checler F, Kuroda S.

Neurosci Lett. 2003 Jun 12;343(3):175-9.

PMID:
12770691
11.

Olfactory involvement in aging and Alzheimer's disease: an autopsy study.

Attems J, Lintner F, Jellinger KA.

J Alzheimers Dis. 2005 Apr;7(2):149-57; discussion 173-80.

PMID:
15851853
12.

Effects of concentrated ambient particles on normal and hypersecretory airways in rats.

Harkema JR, Keeler G, Wagner J, Morishita M, Timm E, Hotchkiss J, Marsik F, Dvonch T, Kaminski N, Barr E.

Res Rep Health Eff Inst. 2004 Aug;(120):1-68; discussion 69-79.

PMID:
15543855
13.

[beta-amyloidogenesis].

Ihara Y.

Rinsho Shinkeigaku. 1997 Dec;37(12):1100-1. Japanese.

PMID:
9577656
15.

Cellular distribution of insulin-like growth factor-II/mannose-6-phosphate receptor in normal human brain and its alteration in Alzheimer's disease pathology.

Kar S, Poirier J, Guevara J, Dea D, Hawkes C, Robitaille Y, Quirion R.

Neurobiol Aging. 2006 Feb;27(2):199-210. Epub 2005 Apr 9.

PMID:
16399207
16.

Consequence of Abeta immunization on the vasculature of human Alzheimer's disease brain.

Boche D, Zotova E, Weller RO, Love S, Neal JW, Pickering RM, Wilkinson D, Holmes C, Nicoll JA.

Brain. 2008 Dec;131(Pt 12):3299-310. doi: 10.1093/brain/awn261. Epub 2008 Oct 25.

PMID:
18953056
17.

1-(3',4'-Dichloro-2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid (CHF5074), a novel gamma-secretase modulator, reduces brain beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease without causing peripheral toxicity.

Imbimbo BP, Del Giudice E, Colavito D, D'Arrigo A, Dalle Carbonare M, Villetti G, Facchinetti F, Volta R, Pietrini V, Baroc MF, Serneels L, De Strooper B, Leon A.

J Pharmacol Exp Ther. 2007 Dec;323(3):822-30. Epub 2007 Sep 25.

PMID:
17895400
18.

Multiple sclerosis and Alzheimer's disease.

Dal Bianco A, Bradl M, Frischer J, Kutzelnigg A, Jellinger K, Lassmann H.

Ann Neurol. 2008 Feb;63(2):174-83.

PMID:
17924575
19.

Neuronal pentraxin 1 contributes to the neuronal damage evoked by amyloid-beta and is overexpressed in dystrophic neurites in Alzheimer's brain.

Abad MA, Enguita M, DeGregorio-Rocasolano N, Ferrer I, Trullas R.

J Neurosci. 2006 Dec 6;26(49):12735-47.

20.

Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain.

Pasinetti GM, Aisen PS.

Neuroscience. 1998 Nov;87(2):319-24.

PMID:
9740394

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