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Items: 1 to 20 of 125

1.

Parasite-specific eIF2 (eukaryotic initiation factor-2) kinase required for stress-induced translation control.

Sullivan WJ Jr, Narasimhan J, Bhatti MM, Wek RC.

Biochem J. 2004 Jun 1;380(Pt 2):523-31.

2.

GCN2-like eIF2α kinase manages the amino acid starvation response in Toxoplasma gondii.

Konrad C, Wek RC, Sullivan WJ Jr.

Int J Parasitol. 2014 Feb;44(2):139-46. doi: 10.1016/j.ijpara.2013.08.005. Epub 2013 Oct 12.

3.

A GCN2-like eukaryotic initiation factor 2 kinase increases the viability of extracellular Toxoplasma gondii parasites.

Konrad C, Wek RC, Sullivan WJ Jr.

Eukaryot Cell. 2011 Nov;10(11):1403-12. doi: 10.1128/EC.05117-11. Epub 2011 Sep 9.

4.

Translation regulation by eukaryotic initiation factor-2 kinases in the development of latent cysts in Toxoplasma gondii.

Narasimhan J, Joyce BR, Naguleswaran A, Smith AT, Livingston MR, Dixon SE, Coppens I, Wek RC, Sullivan WJ Jr.

J Biol Chem. 2008 Jun 13;283(24):16591-601. doi: 10.1074/jbc.M800681200. Epub 2008 Apr 16.

5.

Effects of PERK eIF2α kinase inhibitor against Toxoplasma gondii.

Augusto L, Martynowicz J, Staschke KA, Wek RC, Sullivan WJ Jr.

Antimicrob Agents Chemother. 2018 Sep 4. pii: AAC.01442-18. doi: 10.1128/AAC.01442-18. [Epub ahead of print]

PMID:
30181373
6.
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8.

Methods for analyzing eIF2 kinases and translational control in the unfolded protein response.

Teske BF, Baird TD, Wek RC.

Methods Enzymol. 2011;490:333-56. doi: 10.1016/B978-0-12-385114-7.00019-2.

PMID:
21266259
9.

PKR and GCN2 kinases and guanine nucleotide exchange factor eukaryotic translation initiation factor 2B (eIF2B) recognize overlapping surfaces on eIF2alpha.

Dey M, Trieselmann B, Locke EG, Lu J, Cao C, Dar AC, Krishnamoorthy T, Dong J, Sicheri F, Dever TE.

Mol Cell Biol. 2005 Apr;25(8):3063-75.

10.

PfeIK1, a eukaryotic initiation factor 2alpha kinase of the human malaria parasite Plasmodium falciparum, regulates stress-response to amino-acid starvation.

Fennell C, Babbitt S, Russo I, Wilkes J, Ranford-Cartwright L, Goldberg DE, Doerig C.

Malar J. 2009 May 12;8:99. doi: 10.1186/1475-2875-8-99.

11.

Toxoplasma gondii Cyclic AMP-Dependent Protein Kinase Subunit 3 Is Involved in the Switch from Tachyzoite to Bradyzoite Development.

Sugi T, Ma YF, Tomita T, Murakoshi F, Eaton MS, Yakubu R, Han B, Tu V, Kato K, Kawazu S, Gupta N, Suvorova ES, White MW, Kim K, Weiss LM.

MBio. 2016 May 31;7(3). pii: e00755-16. doi: 10.1128/mBio.00755-16.

12.

The unfolded protein response in the protozoan parasite Toxoplasma gondii features translational and transcriptional control.

Joyce BR, Tampaki Z, Kim K, Wek RC, Sullivan WJ Jr.

Eukaryot Cell. 2013 Jul;12(7):979-89. doi: 10.1128/EC.00021-13. Epub 2013 May 10.

13.

Phosphorylation of eukaryotic initiation factor-2{alpha} promotes the extracellular survival of obligate intracellular parasite Toxoplasma gondii.

Joyce BR, Queener SF, Wek RC, Sullivan WJ Jr.

Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17200-5. doi: 10.1073/pnas.1007610107. Epub 2010 Sep 20.

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Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase.

Harding HP, Zhang Y, Ron D.

Nature. 1999 Jan 21;397(6716):271-4. Erratum in: Nature 1999 Mar 4;398(6722):90.

PMID:
9930704
17.
18.

eIF2 and the control of cell physiology.

Proud CG.

Semin Cell Dev Biol. 2005 Feb;16(1):3-12. Epub 2004 Dec 10. Review.

PMID:
15659334

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