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Items: 1 to 20 of 109

1.

Hepatitis C virus core functions as a suppressor of cyclin-dependent kinase-activating kinase and impairs cell cycle progression.

Ohkawa K, Ishida H, Nakanishi F, Hosui A, Ueda K, Takehara T, Hori M, Hayashi N.

J Biol Chem. 2004 Mar 19;279(12):11719-26. Epub 2004 Jan 7.

2.

Role of p38 MAPK and RNA-dependent protein kinase (PKR) in hepatitis C virus core-dependent nuclear delocalization of cyclin B1.

Spaziani A, Alisi A, Sanna D, Balsano C.

J Biol Chem. 2006 Apr 21;281(16):10983-9. Epub 2006 Jan 30.

3.

Is Cdk7/cyclin H/MAT1 the genuine cdk activating kinase in cycling Xenopus egg extracts?

Fesquet D, Morin N, Doree M, Devault A.

Oncogene. 1997 Sep;15(11):1303-7.

4.

Hepatitis C virus core protein selectively inhibits synthesis and accumulation of p21/Waf1 and certain nuclear proteins.

Oka K, Nagano-Fujii M, Yoshida I, Hidajat R, Deng L, Akutsu M, Hotta H.

Microbiol Immunol. 2003;47(6):429-38.

5.

Activation of the CKI-CDK-Rb-E2F pathway in full genome hepatitis C virus-expressing cells.

Tsukiyama-Kohara K, Toné S, Maruyama I, Inoue K, Katsume A, Nuriya H, Ohmori H, Ohkawa J, Taira K, Hoshikawa Y, Shibasaki F, Reth M, Minatogawa Y, Kohara M.

J Biol Chem. 2004 Apr 9;279(15):14531-41. Epub 2004 Jan 26.

6.

HCV NS2 protein inhibits cell proliferation and induces cell cycle arrest in the S-phase in mammalian cells through down-regulation of cyclin A expression.

Yang XJ, Liu J, Ye L, Liao QJ, Wu JG, Gao JR, She YL, Wu ZH, Ye LB.

Virus Res. 2006 Nov;121(2):134-43. Epub 2006 Jun 23.

PMID:
16797769
7.

Regulation of CDK7 substrate specificity by MAT1 and TFIIH.

Yankulov KY, Bentley DL.

EMBO J. 1997 Apr 1;16(7):1638-46.

8.

Hepatitis C virus core protein represses p21WAF1/Cip1/Sid1 promoter activity.

Ray RB, Steele R, Meyer K, Ray R.

Gene. 1998 Feb 27;208(2):331-6.

PMID:
9524287
9.

Hepatitis C virus core protein induces apoptosis and impairs cell-cycle regulation in stably transformed Chinese hamster ovary cells.

Honda M, Kaneko S, Shimazaki T, Matsushita E, Kobayashi K, Ping LH, Zhang HC, Lemon SM.

Hepatology. 2000 Jun;31(6):1351-9.

PMID:
10827163
10.
12.

In vitro and in vivo activity of R547: a potent and selective cyclin-dependent kinase inhibitor currently in phase I clinical trials.

DePinto W, Chu XJ, Yin X, Smith M, Packman K, Goelzer P, Lovey A, Chen Y, Qian H, Hamid R, Xiang Q, Tovar C, Blain R, Nevins T, Higgins B, Luistro L, Kolinsky K, Felix B, Hussain S, Heimbrook D.

Mol Cancer Ther. 2006 Nov;5(11):2644-58.

14.

Fission yeast Csk1 is a CAK-activating kinase (CAKAK).

Hermand D, Pihlak A, Westerling T, Damagnez V, Vandenhaute J, Cottarel G, Mäkelä TP.

EMBO J. 1998 Dec 15;17(24):7230-8.

15.

Suppression of ceramide-induced cell death by hepatitis C virus core protein.

Kim JS, Ryu J, Hwang SB, Lee SY, Choi SY, Park J.

J Biochem Mol Biol. 2004 Mar 31;37(2):192-8.

PMID:
15469695
16.

Cyclins and CDKS in development and cancer: lessons from genetically modified mice.

Santamaria D, Ortega S.

Front Biosci. 2006 Jan 1;11:1164-88. Review.

PMID:
16146805
17.

Cell cycle perturbation in the hepatocytes of HCV core transgenic mice following common bile duct ligation is associated with enhanced p21 expression.

Chang ML, Chen TH, Chang MY, Yeh CT.

J Med Virol. 2009 Mar;81(3):467-72. doi: 10.1002/jmv.21403.

PMID:
19152410
18.

Hepatitis C virus core protein promotes cell proliferation through the upregulation of cyclin E expression levels.

Cho JW, Baek WK, Suh SI, Yang SH, Chang J, Sung YC, Suh MH.

Liver. 2001 Apr;21(2):137-42.

PMID:
11318983
19.

Cyclin H is targeted to the nucleus by C-terminal nuclear localization sequences.

Krempler A, Kartarius S, Günther J, Montenarh M.

Cell Mol Life Sci. 2005 Jun;62(12):1379-87.

PMID:
15971111
20.

Thr 446 phosphorylation of PKR by HCV core protein deregulates G2/M phase in HCC cells.

Alisi A, Mele R, Spaziani A, Tavolaro S, Palescandolo E, Balsano C.

J Cell Physiol. 2005 Oct;205(1):25-31.

PMID:
15880455

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