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Items: 1 to 20 of 139

1.

HCV NS5A interacts with p53 and inhibits p53-mediated apoptosis.

Lan KH, Sheu ML, Hwang SJ, Yen SH, Chen SY, Wu JC, Wang YJ, Kato N, Omata M, Chang FY, Lee SD.

Oncogene. 2002 Jul 18;21(31):4801-11.

2.

HCV core, NS3, NS5A and NS5B proteins modulate cell proliferation independently from p53 expression in hepatocarcinoma cell lines.

Siavoshian S, Abraham JD, Kieny MP, Schuster C.

Arch Virol. 2004 Feb;149(2):323-36. Epub 2003 Sep 22.

PMID:
14745598
3.

The oncogenic role of NS5A of hepatitis C virus is mediated by up-regulation of survivin gene expression in the hepatocellular cell through p53 and NF-κB pathways.

Jiang YF, He B, Li NP, Ma J, Gong GZ, Zhang M.

Cell Biol Int. 2011 Dec;35(12):1225-32. doi: 10.1042/CBI20110102.

PMID:
21612579
5.

[Molecular mechanism of HCV NS5A on p53's inhibition of AFP expression in hepatocellular carcinoma cells].

Gong GZ, Jiang YF, He Y, Lai LY, Xu Y, Su XS.

Zhonghua Gan Zang Bing Za Zhi. 2005 Jul;13(7):505-8. Chinese.

PMID:
16042885
6.

The Hepatitis C virus NS5A protein activates a phosphoinositide 3-kinase-dependent survival signaling cascade.

Street A, Macdonald A, Crowder K, Harris M.

J Biol Chem. 2004 Mar 26;279(13):12232-41. Epub 2004 Jan 5.

7.

Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability.

Otsuka M, Kato N, Lan K, Yoshida H, Kato J, Goto T, Shiratori Y, Omata M.

J Biol Chem. 2000 Nov 3;275(44):34122-30.

8.

Hepatitis C virus NS5A protein impairs TNF-mediated hepatic apoptosis, but not by an anti-FAS antibody, in transgenic mice.

Majumder M, Ghosh AK, Steele R, Zhou XY, Phillips NJ, Ray R, Ray RB.

Virology. 2002 Mar 1;294(1):94-105.

9.

[Regulation mechanism of HCV NS5A on p53 protein transactivity].

Gong GZ, Jiang YF, Zhu YH, Su XS.

Zhonghua Gan Zang Bing Za Zhi. 2003 Mar;11(3):162-5. Chinese.

PMID:
12681065
10.

Activation of p53 tumor suppressor by hepatitis C virus core protein.

Lu W, Lo SY, Chen M, Wu Kj, Fung YK, Ou JH.

Virology. 1999 Nov 10;264(1):134-41.

11.

Wild-type p53 induces apoptosis in Hep3B through up-regulation of bax expression.

Mitry RR, Sarraf CE, Wu CG, Pignatelli M, Habib NA.

Lab Invest. 1997 Oct;77(4):369-78.

PMID:
9354771
12.

[Effects of hepatitis B virus X gene on p21(WAF1) expression through p53-dependent and p53-independent pathways].

Lin J, Zhu MH, Qu JH, Li FM, Ni CR.

Ai Zheng. 2004 Jul;23(7):749-55. Chinese.

PMID:
15248906
13.

The cytotoxic effect of E1B 55-kDa mutant adenovirus on human hepatocellular carcinoma cell lines.

Zhao J, Wang H, Wei L, Habib NA, Lu X, Wu M, Guo Y.

Cancer Gene Ther. 2001 May;8(5):333-41.

14.

Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins.

Shi ST, Polyak SJ, Tu H, Taylor DR, Gretch DR, Lai MM.

Virology. 2002 Jan 20;292(2):198-210.

15.

ING1 represses transcription by direct DNA binding and through effects on p53.

Kataoka H, Bonnefin P, Vieyra D, Feng X, Hara Y, Miura Y, Joh T, Nakabayashi H, Vaziri H, Harris CC, Riabowol K.

Cancer Res. 2003 Sep 15;63(18):5785-92.

16.

Hepatitis C virus non-structural protein NS5A interacts with FKBP38 and inhibits apoptosis in Huh7 hepatoma cells.

Wang J, Tong W, Zhang X, Chen L, Yi Z, Pan T, Hu Y, Xiang L, Yuan Z.

FEBS Lett. 2006 Aug 7;580(18):4392-400. Epub 2006 Jul 17.

17.

Characterization of a HCV NS5A protein derived from a patient with hepatoma.

Yeh CT, Chang MH, Shyu WC, Chang ML, Yang PY, Tsao ML, Lai HY.

Biochem Biophys Res Commun. 2005 Feb 11;327(2):516-22.

PMID:
15629144
18.

HBV DNA can bind to P53 protein and influence p53 transactivation in hepatoma cells.

Qu J, Lin J, Zhang S, Zhu Z, Ni C, Zhang S, Gao H, Zhu M.

Biochem Biophys Res Commun. 2009 Aug 28;386(3):504-9. doi: 10.1016/j.bbrc.2009.06.081. Epub 2009 Jun 18.

PMID:
19540192
19.

HCV NS5A inhibits interferon-alpha signaling through suppression of STAT1 phosphorylation in hepatocyte-derived cell lines.

Lan KH, Lan KL, Lee WP, Sheu ML, Chen MY, Lee YL, Yen SH, Chang FY, Lee SD.

J Hepatol. 2007 May;46(5):759-67. Epub 2006 Dec 14.

PMID:
17275127
20.

Studies on the role of NS3 and NS5A non-structural genes of hepatitis C virus genotype 3a local isolates in apoptosis.

Sabri S, Idrees M, Rafique S, Ali A, Iqbal M.

Int J Infect Dis. 2014 Aug;25:38-44. doi: 10.1016/j.ijid.2014.01.010. Epub 2014 May 17.

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