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Items: 1 to 20 of 139


Roles of the AX(4)GKS and arginine-rich motifs of hepatitis C virus RNA helicase in ATP- and viral RNA-binding activity.

Chang SC, Cheng JC, Kou YH, Kao CH, Chiu CH, Wu HY, Chang MF.

J Virol. 2000 Oct;74(20):9732-7.


Structure-based mutational analysis of the hepatitis C virus NS3 helicase.

Tai CL, Pan WC, Liaw SH, Yang UC, Hwang LH, Chen DS.

J Virol. 2001 Sep;75(17):8289-97.


In vitro selection of RNA aptamers against the HCV NS3 helicase domain.

Nishikawa F, Funaji K, Fukuda K, Nishikawa S.

Oligonucleotides. 2004;14(2):114-29.


Hepatitis C virus NS3 RNA helicase activity is modulated by the two domains of NS3 and NS4A.

Kuang WF, Lin YC, Jean F, Huang YW, Tai CL, Chen DS, Chen PJ, Hwang LH.

Biochem Biophys Res Commun. 2004 Apr 23;317(1):211-7.


Nucleoside triphosphatase and RNA helicase activities associated with GB virus B nonstructural protein 3.

Zhong W, Ingravallo P, Wright-Minogue J, Skelton A, Uss AS, Chase R, Yao N, Lau JY, Hong Z.

Virology. 1999 Sep 1;261(2):216-26.


Use of the fused NS4A peptide-NS3 protease domain to study the importance of the helicase domain for protease inhibitor binding to hepatitis C virus NS3-NS4A.

Thibeault D, Massariol MJ, Zhao S, Welchner E, Goudreau N, Gingras R, Llinàs-Brunet M, White PW.

Biochemistry. 2009 Feb 3;48(4):744-53. doi: 10.1021/bi801931e.


The interdomain interface in bifunctional enzyme protein 3/4A (NS3/4A) regulates protease and helicase activities.

Aydin C, Mukherjee S, Hanson AM, Frick DN, Schiffer CA.

Protein Sci. 2013 Dec;22(12):1786-98. doi: 10.1002/pro.2378. Epub 2013 Oct 19.


Unmasking the active helicase conformation of nonstructural protein 3 from hepatitis C virus.

Ding SC, Kohlway AS, Pyle AM.

J Virol. 2011 May;85(9):4343-53. doi: 10.1128/JVI.02130-10. Epub 2011 Feb 16.


Functional interactions between conserved motifs of the hepatitis C virus RNA helicase protein NS3.

Min KH, Sung YC, Choi SY, Ahn BY.

Virus Genes. 1999;19(1):33-43.


Virus-specific cofactor requirement and chimeric hepatitis C virus/GB virus B nonstructural protein 3.

Butkiewicz N, Yao N, Zhong W, Wright-Minogue J, Ingravallo P, Zhang R, Durkin J, Standring DN, Baroudy BM, Sangar DV, Lemon SM, Lau JY, Hong Z.

J Virol. 2000 May;74(9):4291-301.


The NTPase/helicase domain of hepatitis C virus nonstructural protein 3 inhibits protein kinase C independently of its NTPase activity.

Hartjen P, Höchst B, Heim D, von der Kammer H, Lucke J, Reinholz M, Baier A, Smeets R, Wege H, Borowski P, Schulze Zur Wiesch J.

Cell Mol Biol Lett. 2013 Sep;18(3):447-58. doi: 10.2478/s11658-013-0099-7. Epub 2013 Jul 27.


Mutational analysis of the hepatitis C virus RNA helicase.

Kim DW, Kim J, Gwack Y, Han JH, Choe J.

J Virol. 1997 Dec;71(12):9400-9.


A novel recombinant single-chain hepatitis C virus NS3-NS4A protein with improved helicase activity.

Howe AY, Chase R, Taremi SS, Risano C, Beyer B, Malcolm B, Lau JY.

Protein Sci. 1999 Jun;8(6):1332-41.


The acidic sequence of the NS4A cofactor regulates ATP hydrolysis by the HCV NS3 helicase.

Shiryaev SA, Chernov AV, Shiryaeva TN, Aleshin AE, Strongin AY.

Arch Virol. 2011 Feb;156(2):313-8. doi: 10.1007/s00705-010-0838-2. Epub 2010 Oct 27.


Two novel conserved motifs in the hepatitis C virus NS3 protein critical for helicase action.

Lam AM, Keeney D, Frick DN.

J Biol Chem. 2003 Nov 7;278(45):44514-24. Epub 2003 Aug 27.

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