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Items: 1 to 20 of 59

1.

Modulation of cell growth by the hepatitis C virus nonstructural protein NS5A.

Arima N, Kao CY, Licht T, Padmanabhan R, Sasaguri Y, Padmanabhan R.

J Biol Chem. 2001 Apr 20;276(16):12675-84. Epub 2001 Jan 19.

2.

Characterization of the effects of hepatitis C virus nonstructural 5A protein expression in human cell lines and on interferon-sensitive virus replication.

Polyak SJ, Paschal DM, McArdle S, Gale MJ Jr, Moradpour D, Gretch DR.

Hepatology. 1999 Apr;29(4):1262-71.

PMID:
10094974
3.

HCV NS2 protein inhibits cell proliferation and induces cell cycle arrest in the S-phase in mammalian cells through down-regulation of cyclin A expression.

Yang XJ, Liu J, Ye L, Liao QJ, Wu JG, Gao JR, She YL, Wu ZH, Ye LB.

Virus Res. 2006 Nov;121(2):134-43. Epub 2006 Jun 23.

PMID:
16797769
4.

Suppression of the ERK1/2 signaling pathway from HCV NS5A protein expressed by herpes simplex recombinant viruses.

Georgopoulou U, Caravokiri K, Mavromara P.

Arch Virol. 2003 Feb;148(2):237-51.

PMID:
12556990
5.

NS1- and minute virus of mice-induced cell cycle arrest: involvement of p53 and p21(cip1).

Op De Beeck A, Sobczak-Thepot J, Sirma H, Bourgain F, Brechot C, Caillet-Fauquet P.

J Virol. 2001 Nov;75(22):11071-8.

6.

Hepatitis C virus NS5A protein down-regulates the expression of spindle gene Aspm through PKR-p38 signaling pathway.

Wu SC, Chang SC, Wu HY, Liao PJ, Chang MF.

J Biol Chem. 2008 Oct 24;283(43):29396-404. doi: 10.1074/jbc.M802821200. Epub 2008 Aug 26.

7.

The protein phosphatase 2A represents a novel cellular target for hepatitis C virus NS5A protein.

Georgopoulou U, Tsitoura P, Kalamvoki M, Mavromara P.

Biochimie. 2006 Jun;88(6):651-62. Epub 2006 Jan 18.

PMID:
16460864
8.

HCV NS5A interacts with p53 and inhibits p53-mediated apoptosis.

Lan KH, Sheu ML, Hwang SJ, Yen SH, Chen SY, Wu JC, Wang YJ, Kato N, Omata M, Chang FY, Lee SD.

Oncogene. 2002 Jul 18;21(31):4801-11.

9.

HCV core, NS3, NS5A and NS5B proteins modulate cell proliferation independently from p53 expression in hepatocarcinoma cell lines.

Siavoshian S, Abraham JD, Kieny MP, Schuster C.

Arch Virol. 2004 Feb;149(2):323-36. Epub 2003 Sep 22.

PMID:
14745598
10.

Positive effect of the hepatitis C virus nonstructural 5A protein on viral multiplication.

Bonte D, Fran├žois C, Castelain S, Wychowski C, Dubuisson J, Meurs EF, Duverlie G.

Arch Virol. 2004 Jul;149(7):1353-71. Epub 2004 Mar 17.

PMID:
15221536
11.

Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins.

Shi ST, Polyak SJ, Tu H, Taylor DR, Gretch DR, Lai MM.

Virology. 2002 Jan 20;292(2):198-210.

12.

A link between translation of the hepatitis C virus polyprotein and polymerase function; possible consequences for hyperphosphorylation of NS5A.

McCormick CJ, Brown D, Griffin S, Challinor L, Rowlands DJ, Harris M.

J Gen Virol. 2006 Jan;87(Pt 1):93-102.

PMID:
16361421
13.

Hepatitis B virus X protein differentially regulates cell cycle progression in X-transforming versus nontransforming hepatocyte (AML12) cell lines.

Lee S, Tarn C, Wang WH, Chen S, Hullinger RL, Andrisani OM.

J Biol Chem. 2002 Mar 8;277(10):8730-40. Epub 2001 Dec 26.

14.

p53-independent expression of p21(CIP1/WAF1) in plasmacytic cells during G(2) cell cycle arrest induced by Actinobacillus actinomycetemcomitans cytolethal distending toxin.

Sato T, Koseki T, Yamato K, Saiki K, Konishi K, Yoshikawa M, Ishikawa I, Nishihara T.

Infect Immun. 2002 Feb;70(2):528-34.

15.

Hepatitis C virus NS5A protein modulates cell cycle regulatory genes and promotes cell growth.

Ghosh AK, Steele R, Meyer K, Ray R, Ray RB.

J Gen Virol. 1999 May;80 ( Pt 5):1179-83.

PMID:
10355764
16.

Hepatitis C virus NS5A protein is phosphorylated by casein kinase II.

Kim J, Lee D, Choe J.

Biochem Biophys Res Commun. 1999 Apr 21;257(3):777-81.

PMID:
10208859
17.

Phosphorylation of hepatitis C virus NS5A nonstructural protein: a new paradigm for phosphorylation-dependent viral RNA replication?

Huang Y, Staschke K, De Francesco R, Tan SL.

Virology. 2007 Jul 20;364(1):1-9. Epub 2007 Apr 2. Review.

18.

Effects of mutation in hepatitis C virus nonstructural protein 5A on interferon resistance mediated by inhibition of PKR kinase activity in mammalian cells.

Noguchi T, Satoh S, Noshi T, Hatada E, Fukuda R, Kawai A, Ikeda S, Hijikata M, Shimotohno K.

Microbiol Immunol. 2001;45(12):829-40. Erratum in: Microbiol Immunol. 2002;46(4):305.

19.

Inhibition of hepatitis C virus protein expression by RNA interference.

Sen A, Steele R, Ghosh AK, Basu A, Ray R, Ray RB.

Virus Res. 2003 Oct;96(1-2):27-35.

PMID:
12951263
20.

Hepatitis C virus NS5A protein impairs TNF-mediated hepatic apoptosis, but not by an anti-FAS antibody, in transgenic mice.

Majumder M, Ghosh AK, Steele R, Zhou XY, Phillips NJ, Ray R, Ray RB.

Virology. 2002 Mar 1;294(1):94-105.

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