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Items: 1 to 20 of 129

1.

Influenza virus propagation is impaired by inhibition of the Raf/MEK/ERK signalling cascade.

Pleschka S, Wolff T, Ehrhardt C, Hobom G, Planz O, Rapp UR, Ludwig S.

Nat Cell Biol. 2001 Mar;3(3):301-5.

PMID:
11231581
2.

MEK inhibition impairs influenza B virus propagation without emergence of resistant variants.

Ludwig S, Wolff T, Ehrhardt C, Wurzer WJ, Reinhardt J, Planz O, Pleschka S.

FEBS Lett. 2004 Mar 12;561(1-3):37-43.

3.

c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells.

Iijima Y, Laser M, Shiraishi H, Willey CD, Sundaravadivel B, Xu L, McDermott PJ, Kuppuswamy D.

J Biol Chem. 2002 Jun 21;277(25):23065-75. Epub 2002 Apr 8.

4.

MEK-specific inhibitor U0126 blocks spread of Borna disease virus in cultured cells.

Planz O, Pleschka S, Ludwig S.

J Virol. 2001 May;75(10):4871-7.

5.

Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.

Yip-Schneider MT, Klein PJ, Wentz SC, Zeni A, Menze A, Schmidt CM.

J Pharmacol Exp Ther. 2009 Jun;329(3):1063-70. doi: 10.1124/jpet.108.147306. Epub 2009 Mar 3.

6.

Neurotensin stimulates protein kinase C-dependent mitogenic signaling in human pancreatic carcinoma cell line PANC-1.

Guha S, Lunn JA, Santiskulvong C, Rozengurt E.

Cancer Res. 2003 May 15;63(10):2379-87.

7.
9.

MEK inhibition of pancreatic carcinoma cells by U0126 and its effect in combination with sulindac.

Yip-Schneider MT, Schmidt CM.

Pancreas. 2003 Nov;27(4):337-44.

PMID:
14576498
10.
11.

Activation and role of MAP kinase-dependent pathways in retinal pigment epithelial cells: ERK and RPE cell proliferation.

Hecquet C, Lefevre G, Valtink M, Engelmann K, Mascarelli F.

Invest Ophthalmol Vis Sci. 2002 Sep;43(9):3091-8.

PMID:
12202534
12.

MEK/ERK pathway is aberrantly active in Hodgkin disease: a signaling pathway shared by CD30, CD40, and RANK that regulates cell proliferation and survival.

Zheng B, Fiumara P, Li YV, Georgakis G, Snell V, Younes M, Vauthey JN, Carbone A, Younes A.

Blood. 2003 Aug 1;102(3):1019-27. Epub 2003 Apr 10.

13.

Aryl hydrocarbon receptor activation and cytochrome P450 1A induction by the mitogen-activated protein kinase inhibitor U0126 in hepatocytes.

Andrieux L, Langou√ęt S, Fautrel A, Ezan F, Krauser JA, Savouret JF, Guengerich FP, Baffet G, Guillouzo A.

Mol Pharmacol. 2004 Apr;65(4):934-43.

14.

Functional interactions of Raf and MEK with Jun-N-terminal kinase (JNK) result in a positive feedback loop on the oncogenic Ras signaling pathway.

Adler V, Qu Y, Smith SJ, Izotova L, Pestka S, Kung HF, Lin M, Friedman FK, Chie L, Chung D, Boutjdir M, Pincus MR.

Biochemistry. 2005 Aug 16;44(32):10784-95.

PMID:
16086581
15.
16.

Inhibition of influenza virus-induced NF-kappaB and Raf/MEK/ERK activation can reduce both virus titers and cytokine expression simultaneously in vitro and in vivo.

Pinto R, Herold S, Cakarova L, Hoegner K, Lohmeyer J, Planz O, Pleschka S.

Antiviral Res. 2011 Oct;92(1):45-56. doi: 10.1016/j.antiviral.2011.05.009. Epub 2011 May 27.

PMID:
21641936
18.

Hepatocyte growth factor/scatter factor activates the ETS1 transcription factor by a RAS-RAF-MEK-ERK signaling pathway.

Paumelle R, Tulasne D, Kherrouche Z, Plaza S, Leroy C, Reveneau S, Vandenbunder B, Fafeur V.

Oncogene. 2002 Apr 4;21(15):2309-19. Erratum in: Oncogene 2002 Jul 18;21(31):4872. Tulashe, David [corrected to Tulasne, David]; Reveneau, Syline [corrected to Reveneau, Sylvie].

19.

Inhibition of the Raf/MEK/ERK pathway up-regulates expression of the coxsackievirus and adenovirus receptor in cancer cells.

Anders M, Christian C, McMahon M, McCormick F, Korn WM.

Cancer Res. 2003 May 1;63(9):2088-95.

20.

Thrombin-stimulated cell proliferation mediated through activation of Ras/Raf/MEK/MAPK pathway in canine cultured tracheal smooth muscle cells.

Lin CC, Shyr MH, Chien CS, Wang CC, Chiu CT, Hsiao LD, Yang CM.

Cell Signal. 2002 Mar;14(3):265-75.

PMID:
11812655

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