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Items: 1 to 20 of 98

1.

Nonstructural protein 5A of hepatitis C virus inhibits the function of karyopherin beta3.

Chung KM, Lee J, Kim JE, Song OK, Cho S, Lim J, Seedorf M, Hahm B, Jang SK.

J Virol. 2000 Jun;74(11):5233-41.

2.

A novel function of karyopherin beta3 associated with apolipoprotein A-I secretion.

Chung KM, Cha SS, Jang SK.

Mol Cells. 2008 Sep 30;26(3):291-8. Epub 2008 Jun 18.

3.

Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation.

Gale M Jr, Blakely CM, Kwieciszewski B, Tan SL, Dossett M, Tang NM, Korth MJ, Polyak SJ, Gretch DR, Katze MG.

Mol Cell Biol. 1998 Sep;18(9):5208-18.

5.

Genetic complementation of hepatitis C virus nonstructural protein functions associated with replication exhibits requirements that differ from those for virion assembly.

Herod MR, Schregel V, Hinds C, Liu M, McLauchlan J, McCormick CJ.

J Virol. 2014 Mar;88(5):2748-62. doi: 10.1128/JVI.03588-13. Epub 2013 Dec 18.

6.

Regulation of hepatitis C virus replication by nuclear translocation of nonstructural 5A protein and transcriptional activation of host genes.

Maqbool MA, Imache MR, Higgs MR, Carmouse S, Pawlotsky JM, Lerat H.

J Virol. 2013 May;87(10):5523-39. doi: 10.1128/JVI.00585-12. Epub 2013 Mar 6. Erratum in: J Virol. 2013 Sep;87(17):9963.

7.

Vinexin β Interacts with Hepatitis C Virus NS5A, Modulating Its Hyperphosphorylation To Regulate Viral Propagation.

Xiong W, Yang J, Wang M, Wang H, Rao Z, Zhong C, Xin X, Mo L, Yu S, Shen C, Zheng C.

J Virol. 2015 Jul;89(14):7385-400. doi: 10.1128/JVI.00567-15. Epub 2015 May 13.

8.

The SH3 binding motif of HCV [corrected] NS5A protein interacts with Bin1 and is important for apoptosis and infectivity.

Nanda SK, Herion D, Liang TJ.

Gastroenterology. 2006 Mar;130(3):794-809. Erratum in: Gastroenterology. 2006 Aug;131(2):687.

PMID:
16530520
9.

Hepatitis C virus RNA polymerase and NS5A complex with a SNARE-like protein.

Tu H, Gao L, Shi ST, Taylor DR, Yang T, Mircheff AK, Wen Y, Gorbalenya AE, Hwang SB, Lai MM.

Virology. 1999 Oct 10;263(1):30-41.

10.

Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein.

Gale MJ Jr, Korth MJ, Tang NM, Tan SL, Hopkins DA, Dever TE, Polyak SJ, Gretch DR, Katze MG.

Virology. 1997 Apr 14;230(2):217-27.

11.

Hepatitis C virus NS5A colocalizes with the core protein on lipid droplets and interacts with apolipoproteins.

Shi ST, Polyak SJ, Tu H, Taylor DR, Gretch DR, Lai MM.

Virology. 2002 Jan 20;292(2):198-210.

12.
13.

Hepatitis C virus nonstructural 5A protein induces interleukin-8, leading to partial inhibition of the interferon-induced antiviral response.

Polyak SJ, Khabar KS, Paschal DM, Ezelle HJ, Duverlie G, Barber GN, Levy DE, Mukaida N, Gretch DR.

J Virol. 2001 Jul;75(13):6095-106.

14.

Nonstructural 5A protein activates beta-catenin signaling cascades: implication of hepatitis C virus-induced liver pathogenesis.

Park CY, Choi SH, Kang SM, Kang JI, Ahn BY, Kim H, Jung G, Choi KY, Hwang SB.

J Hepatol. 2009 Nov;51(5):853-64. doi: 10.1016/j.jhep.2009.06.026. Epub 2009 Aug 12.

PMID:
19726098
15.
16.

Hepatitis C Virus Nonstructural 5A Protein Interacts with Abelson Interactor 1 and Modulates Epidermal Growth Factor-mediated MEK/ERK Signaling Pathway.

Huynh VT, Lim YS, Tran SC, Pham TM, Nguyen LN, Hwang SB.

J Biol Chem. 2016 Oct 21;291(43):22607-22617. Epub 2016 Aug 22.

17.

Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein.

Vogt DA, Camus G, Herker E, Webster BR, Tsou CL, Greene WC, Yen TS, Ott M.

PLoS Pathog. 2013;9(4):e1003302. doi: 10.1371/journal.ppat.1003302. Epub 2013 Apr 11.

18.

Y-Box Binding Protein 1 Stabilizes Hepatitis C Virus NS5A via Phosphorylation-Mediated Interaction with NS5A To Regulate Viral Propagation.

Wang WT, Tsai TY, Chao CH, Lai BY, Wu Lee YH.

J Virol. 2015 Nov;89(22):11584-602. doi: 10.1128/JVI.01513-15. Epub 2015 Sep 9.

19.

Repression of the PKR protein kinase by the hepatitis C virus NS5A protein: a potential mechanism of interferon resistance.

Gale MJ Jr, Korth MJ, Katze MG.

Clin Diagn Virol. 1998 Jul 15;10(2-3):157-62. Review.

PMID:
9741641
20.

Characterization of the effects of hepatitis C virus nonstructural 5A protein expression in human cell lines and on interferon-sensitive virus replication.

Polyak SJ, Paschal DM, McArdle S, Gale MJ Jr, Moradpour D, Gretch DR.

Hepatology. 1999 Apr;29(4):1262-71.

PMID:
10094974

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