Format
Sort by
Items per page

Send to

Choose Destination

Links from Protein

Items: 1 to 20 of 298

1.

Bcl3 Phosphorylation by Akt, Erk2, and IKK Is Required for Its Transcriptional Activity.

Wang VY, Li Y, Kim D, Zhong X, Du Q, Ghassemian M, Ghosh G.

Mol Cell. 2017 Aug 3;67(3):484-497.e5. doi: 10.1016/j.molcel.2017.06.011. Epub 2017 Jul 6.

PMID:
28689659
2.

Akt as a target for cancer therapy: more is not always better (lessons from studies in mice).

Wang Q, Chen X, Hay N.

Br J Cancer. 2017 Jul 11;117(2):159-163. doi: 10.1038/bjc.2017.153. Epub 2017 May 30. Review.

3.

Constitutive Activation of AKT2 in Humans Leads to Hypoglycemia Without Fatty Liver or Metabolic Dyslipidemia.

Minic M, Rocha N, Harris J, Groeneveld MP, Leiter S, Wareham N, Sleigh A, De Lonlay P, Hussain K, O'Rahilly S, Semple RK.

J Clin Endocrinol Metab. 2017 Aug 1;102(8):2914-2921. doi: 10.1210/jc.2017-00768.

PMID:
28541532
4.

Architecture of the human interactome defines protein communities and disease networks.

Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW.

Nature. 2017 May 25;545(7655):505-509. doi: 10.1038/nature22366. Epub 2017 May 17.

5.

AKT2 Regulates Pulmonary Inflammation and Fibrosis via Modulating Macrophage Activation.

Nie Y, Sun L, Wu Y, Yang Y, Wang J, He H, Hu Y, Chang Y, Liang Q, Zhu J, Ye RD, Christman JW, Qian F.

J Immunol. 2017 Jun 1;198(11):4470-4480. doi: 10.4049/jimmunol.1601503. Epub 2017 Apr 28.

PMID:
28455433
6.

A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.

Manning A, Highland HM, Gasser J, Sim X, Tukiainen T, Fontanillas P, Grarup N, Rivas MA, Mahajan A, Locke AE, Cingolani P, Pers TH, Viñuela A, Brown AA, Wu Y, Flannick J, Fuchsberger C, Gamazon ER, Gaulton KJ, Im HK, Teslovich TM, Blackwell TW, Bork-Jensen J, Burtt NP, Chen Y, Green T, Hartl C, Kang HM, Kumar A, Ladenvall C, Ma C, Moutsianas L, Pearson RD, Perry JRB, Rayner NW, Robertson NR, Scott LJ, van de Bunt M, Eriksson JG, Jula A, Koskinen S, Lehtimäki T, Palotie A, Raitakari OT, Jacobs SBR, Wessel J, Chu AY, Scott RA, Goodarzi MO, Blancher C, Buck G, Buck D, Chines PS, Gabriel S, Gjesing AP, Groves CJ, Hollensted M, Huyghe JR, Jackson AU, Jun G, Justesen JM, Mangino M, Murphy J, Neville M, Onofrio R, Small KS, Stringham HM, Trakalo J, Banks E, Carey J, Carneiro MO, DePristo M, Farjoun Y, Fennell T, Goldstein JI, Grant G, Hrabé de Angelis M, Maguire J, Neale BM, Poplin R, Purcell S, Schwarzmayr T, Shakir K, Smith JD, Strom TM, Wieland T, Lindstrom J, Brandslund I, Christensen C, Surdulescu GL, Lakka TA, Doney ASF, Nilsson P, Wareham NJ, Langenberg C, Varga TV, Franks PW, Rolandsson O, Rosengren AH, Farook VS, Thameem F, Puppala S, Kumar S, Lehman DM, Jenkinson CP, Curran JE, Hale DE, Fowler SP, Arya R, DeFronzo RA, Abboud HE, Syvänen AC, Hicks PJ, Palmer ND, Ng MCY, Bowden DW, Freedman BI, Esko T, Mägi R, Milani L, Mihailov E, Metspalu A, Narisu N, Kinnunen L, Bonnycastle LL, Swift A, Pasko D, Wood AR, Fadista J, Pollin TI, Barzilai N, Atzmon G, Glaser B, Thorand B, Strauch K, Peters A, Roden M, Müller-Nurasyid M, Liang L, Kriebel J, Illig T, Grallert H, Gieger C, Meisinger C, Lannfelt L, Musani SK, Griswold M, Taylor HA Jr, Wilson G Sr, Correa A, Oksa H, Scott WR, Afzal U, Tan ST, Loh M, Chambers JC, Sehmi J, Kooner JS, Lehne B, Cho YS, Lee JY, Han BG, Käräjämäki A, Qi Q, Qi L, Huang J, Hu FB, Melander O, Orho-Melander M, Below JE, Aguilar D, Wong TY, Liu J, Khor CC, Chia KS, Lim WY, Cheng CY, Chan E, Tai ES, Aung T, Linneberg A, Isomaa B, Meitinger T, Tuomi T, Hakaste L, Kravic J, Jørgensen ME, Lauritzen T, Deloukas P, Stirrups KE, Owen KR, Farmer AJ, Frayling TM, O'Rahilly SP, Walker M, Levy JC, Hodgkiss D, Hattersley AT, Kuulasmaa T, Stančáková A, Barroso I, Bharadwaj D, Chan J, Chandak GR, Daly MJ, Donnelly PJ, Ebrahim SB, Elliott P, Fingerlin T, Froguel P, Hu C, Jia W, Ma RCW, McVean G, Park T, Prabhakaran D, Sandhu M, Scott J, Sladek R, Tandon N, Teo YY, Zeggini E, Watanabe RM, Koistinen HA, Kesaniemi YA, Uusitupa M, Spector TD, Salomaa V, Rauramaa R, Palmer CNA, Prokopenko I, Morris AD, Bergman RN, Collins FS, Lind L, Ingelsson E, Tuomilehto J, Karpe F, Groop L, Jørgensen T, Hansen T, Pedersen O, Kuusisto J, Abecasis G, Bell GI, Blangero J, Cox NJ, Duggirala R, Seielstad M, Wilson JG, Dupuis J, Ripatti S, Hanis CL, Florez JC, Mohlke KL, Meigs JB, Laakso M, Morris AP, Boehnke M, Altshuler D, McCarthy MI, Gloyn AL, Lindgren CM.

Diabetes. 2017 Jul;66(7):2019-2032. doi: 10.2337/db16-1329. Epub 2017 Mar 24.

PMID:
28341696
7.

Expression of AKT1 along with AKT2 in granulosa-lutein cells of hyperandrogenic PCOS patients.

Nekoonam S, Naji M, Nashtaei MS, Mortezaee K, Koruji M, Safdarian L, Amidi F.

Arch Gynecol Obstet. 2017 Apr;295(4):1041-1050. doi: 10.1007/s00404-017-4317-9. Epub 2017 Mar 7.

PMID:
28271235
8.

MiR-650 inhibits proliferation, migration and invasion of rheumatoid arthritis synovial fibroblasts by targeting AKT2.

Xu X, Chen H, Zhang Q, Xu J, Shi Q, Wang M.

Biomed Pharmacother. 2017 Apr;88:535-541. doi: 10.1016/j.biopha.2017.01.063. Epub 2017 Jan 24.

PMID:
28129626
9.

Role of Akt2 in regulation of metastasis suppressor 1 expression and colorectal cancer metastasis.

Agarwal E, Robb CM, Smith LM, Brattain MG, Wang J, Black JD, Chowdhury S.

Oncogene. 2017 Jun 1;36(22):3104-3118. doi: 10.1038/onc.2016.460. Epub 2017 Jan 9.

PMID:
28068324
10.
11.

Activating the AKT2-nuclear factor-κB-lipocalin-2 axis elicits an inflammatory response in age-related macular degeneration.

Ghosh S, Shang P, Yazdankhah M, Bhutto I, Hose S, Montezuma SR, Luo T, Chattopadhyay S, Qian J, Lutty GA, Ferrington DA, Zigler JS Jr, Sinha D.

J Pathol. 2017 Apr;241(5):583-588. doi: 10.1002/path.4870. Epub 2017 Feb 20.

PMID:
28026019
12.

miR-148a-3p represses proliferation and EMT by establishing regulatory circuits between ERBB3/AKT2/c-myc and DNMT1 in bladder cancer.

Wang X, Liang Z, Xu X, Li J, Zhu Y, Meng S, Li S, Wang S, Xie B, Ji A, Liu B, Zheng X, Xie L.

Cell Death Dis. 2016 Dec 1;7(12):e2503. doi: 10.1038/cddis.2016.373.

13.

miR-148a suppresses human renal cell carcinoma malignancy by targeting AKT2.

Cao H, Liu Z, Wang R, Zhang X, Yi W, Nie G, Yu Y, Wang G, Zhu M.

Oncol Rep. 2017 Jan;37(1):147-154. doi: 10.3892/or.2016.5257. Epub 2016 Nov 18.

PMID:
27878305
14.

Different functions of AKT1 and AKT2 in molecular pathways, cell migration and metabolism in colon cancer cells.

Häggblad Sahlberg S, Mortensen AC, Haglöf J, Engskog MK, Arvidsson T, Pettersson C, Glimelius B, Stenerlöw B, Nestor M.

Int J Oncol. 2017 Jan;50(1):5-14. doi: 10.3892/ijo.2016.3771. Epub 2016 Nov 18.

15.

IRF5 and IRF5 Disease-Risk Variants Increase Glycolysis and Human M1 Macrophage Polarization by Regulating Proximal Signaling and Akt2 Activation.

Hedl M, Yan J, Abraham C.

Cell Rep. 2016 Aug 30;16(9):2442-55. doi: 10.1016/j.celrep.2016.07.060. Epub 2016 Aug 18.

16.

MicroRNAs associated with increased AKT gene number in human lung carcinoma.

Goto A, Dobashi Y, Tsubochi H, Maeda D, Ooi A.

Hum Pathol. 2016 Oct;56:1-10. doi: 10.1016/j.humpath.2016.04.011. Epub 2016 May 14.

PMID:
27189341
17.

SRPK1 and Akt Protein Kinases Phosphorylate the RS Domain of Lamin B Receptor with Distinct Specificity: A Combined Biochemical and In Silico Approach.

Voukkalis N, Koutroumani M, Zarkadas C, Nikolakaki E, Vlassi M, Giannakouros T.

PLoS One. 2016 Apr 22;11(4):e0154198. doi: 10.1371/journal.pone.0154198. eCollection 2016.

18.

Identification and characterization of an hnRNP E1 translational silencing motif.

Brown AS, Mohanty BK, Howe PH.

Nucleic Acids Res. 2016 Jul 8;44(12):5892-907. doi: 10.1093/nar/gkw241. Epub 2016 Apr 11.

19.

Stability and function of adult vasculature is sustained by Akt/Jagged1 signalling axis in endothelium.

Kerr BA, West XZ, Kim YW, Zhao Y, Tischenko M, Cull RM, Phares TW, Peng XD, Bernier-Latmani J, Petrova TV, Adams RH, Hay N, Naga Prasad SV, Byzova TV.

Nat Commun. 2016 Mar 14;7:10960. doi: 10.1038/ncomms10960.

20.

Specific Targeting of Akt Kinase Isoforms: Taking the Precise Path for Prevention and Treatment of Cancer.

Roy NK, Bordoloi D, Monisha J, Padmavathi G, Kotoky J, Golla R, Kunnumakkara AB.

Curr Drug Targets. 2017;18(4):421-435. doi: 10.2174/1389450117666160307145236. Review.

PMID:
26953242

Supplemental Content

Support Center