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Items: 1 to 20 of 715

1.

Activation mechanisms of the E3 ubiquitin ligase parkin.

Panicker N, Dawson VL, Dawson TM.

Biochem J. 2017 Aug 30;474(18):3075-3086. doi: 10.1042/BCJ20170476. Review.

PMID:
28860335
2.

Reduced expression of PARK2 in manganese-exposed smelting workers.

Fan X, Luo Y, Fan Q, Zheng W.

Neurotoxicology. 2017 Sep;62:258-264. doi: 10.1016/j.neuro.2017.08.006. Epub 2017 Aug 18.

3.

Ubiquitin phosphorylated at Ser57 hyper-activates parkin.

George S, Wang SM, Bi Y, Treidlinger M, Barber KR, Shaw GS, O'Donoghue P.

Biochim Biophys Acta. 2017 Nov;1861(11 Pt B):3038-3046. doi: 10.1016/j.bbagen.2017.06.023. Epub 2017 Jul 6.

PMID:
28689991
4.

Inactivation of parkin by promoter methylation correlated with lymph node metastasis and genomic instability in nasopharyngeal carcinoma.

Ni H, Zhou Z, Jiang B, Yuan X, Cao X, Huang G, Li Y.

Tumour Biol. 2017 Mar;39(3):1010428317695025. doi: 10.1177/1010428317695025.

PMID:
28351314
5.

The synaptic function of parkin.

Sassone J, Serratto G, Valtorta F, Silani V, Passafaro M, Ciammola A.

Brain. 2017 Sep 1;140(9):2265-2272. doi: 10.1093/brain/awx006. Review.

PMID:
28335015
6.

A comprehensive computational study on pathogenic mis-sense mutations spanning the RING2 and REP domains of Parkin protein.

Biswas R, Bagchi A.

Gene. 2017 Apr 30;610:49-58. doi: 10.1016/j.gene.2017.02.008. Epub 2017 Feb 9.

PMID:
28189762
7.

Lipid profiling of parkin-mutant human skin fibroblasts.

Lobasso S, Tanzarella P, Vergara D, Maffia M, Cocco T, Corcelli A.

J Cell Physiol. 2017 Dec;232(12):3540-3551. doi: 10.1002/jcp.25815. Epub 2017 Feb 10.

PMID:
28109117
8.

Efficient induction of dopaminergic neuron differentiation from induced pluripotent stem cells reveals impaired mitophagy in PARK2 neurons.

Suzuki S, Akamatsu W, Kisa F, Sone T, Ishikawa KI, Kuzumaki N, Katayama H, Miyawaki A, Hattori N, Okano H.

Biochem Biophys Res Commun. 2017 Jan 29;483(1):88-93. doi: 10.1016/j.bbrc.2016.12.188. Epub 2017 Jan 3.

PMID:
28057485
9.

Definition of a putative pathological region in PARK2 associated with autism spectrum disorder through in silico analysis of its functional structure.

Conceição IC, Rama MM, Oliveira B, Café C, Almeida J, Mouga S, Duque F, Oliveira G, Vicente AM.

Psychiatr Genet. 2017 Apr;27(2):54-61. doi: 10.1097/YPG.0000000000000159.

PMID:
27824727
10.

Second mutation in PARK2 is absent in patients with sporadic Parkinson's disease and heterozygous exonic deletions/duplications in parkin gene.

Shulskaya MV, Shadrina MI, Fedotova EY, Abramycheva NY, Limborska SA, Illarioshkin SN, Slominsky PA.

Int J Neurosci. 2017 Sep;127(9):781-784. doi: 10.1080/00207454.2016.1255612. Epub 2016 Nov 16.

PMID:
27798970
11.

 PARK2 polymorphisms predict disease progression in patients infected with hepatitis C virus.

Al-Qahtani AA, Al-Anazi MR, Al-Zoghaibi FA, Abdo AA, Sanai FM, Al-Hamoudi WK, Alswat KA, Al-Ashgar HI, Khan MQ, Albenmousa A, Khalak H, Al-Ahdal MN.

Ann Hepatol. 2016 Nov-Dec 2016;15(6):824-833.

12.

Impulsive-compulsive behaviors in parkin-associated Parkinson disease.

Morgante F, Fasano A, Ginevrino M, Petrucci S, Ricciardi L, Bove F, Criscuolo C, Moccia M, De Rosa A, Sorbera C, Bentivoglio AR, Barone P, De Michele G, Pellecchia MT, Valente EM.

Neurology. 2016 Oct 4;87(14):1436-1441. Epub 2016 Sep 2.

13.

Preservation Analysis of Macrophage Gene Coexpression Between Human and Mouse Identifies PARK2 as a Genetically Controlled Master Regulator of Oxidative Phosphorylation in Humans.

Codoni V, Blum Y, Civelek M, Proust C, Franzén O; Cardiogenics Consortium; IDEM Leducq Consortium CADGenomics, Björkegren JL, Le Goff W, Cambien F, Lusis AJ, Trégouët DA.

G3 (Bethesda). 2016 Oct 13;6(10):3361-3371. doi: 10.1534/g3.116.033894.

14.

Compartmentalized Regulation of Parkin-Mediated Mitochondrial Quality Control in the Drosophila Nervous System In Vivo.

Sung H, Tandarich LC, Nguyen K, Hollenbeck PJ.

J Neurosci. 2016 Jul 13;36(28):7375-91. doi: 10.1523/JNEUROSCI.0633-16.2016.

15.

Parkin loss-of-function pathology: Premature neuronal senescence induced by high levels of reactive oxygen species?

Buhlman LM.

Mech Ageing Dev. 2017 Jan;161(Pt A):112-120. doi: 10.1016/j.mad.2016.06.008. Epub 2016 Jun 29. Review.

PMID:
27374431
16.

Multiple-level validation identifies PARK2 in the development of lung cancer and chronic obstructive pulmonary disease.

Lee S, She J, Deng B, Kim J, de Andrade M, Na J, Sun Z, Wampfler JA, Cunningham JM, Wu Y, Limper AH, Aubry MC, Wendt C, Biterman P, Yang P, Lou Z.

Oncotarget. 2016 Jul 12;7(28):44211-44223. doi: 10.18632/oncotarget.9954.

17.

Parkin Somatic Mutations Link Melanoma and Parkinson's Disease.

Levin L, Srour S, Gartner J, Kapitansky O, Qutob N, Dror S, Golan T, Dayan R, Brener R, Ziv T, Khaled M, Schueler-Furman O, Samuels Y, Levy C.

J Genet Genomics. 2016 Jun 20;43(6):369-79. doi: 10.1016/j.jgg.2016.05.005. Epub 2016 May 13.

PMID:
27297116
18.

Association of a PARK2 Germline Variant and Epithelial Ovarian Cancer in a Southern Brazilian Population.

Klimczak PF, Ventury DH, Faucz FR, Settas N, Machado de Souza C, Sotomaior VS.

Oncology. 2016;91(2):101-5. doi: 10.1159/000446657. Epub 2016 Jun 10.

19.

A homozygous parkin p.G284R mutation in a Chinese family with autosomal recessive juvenile parkinsonism.

Chen H, Huang X, Yuan L, Xia H, Xu H, Yang Y, Zheng W, Deng H.

Neurosci Lett. 2016 Jun 15;624:100-4. doi: 10.1016/j.neulet.2016.05.011. Epub 2016 May 10.

PMID:
27177722
20.

Genome-wide analysis of copy number variations identifies PARK2 as a candidate gene for autism spectrum disorder.

Yin CL, Chen HI, Li LH, Chien YL, Liao HM, Chou MC, Chou WJ, Tsai WC, Chiu YN, Wu YY, Lo CZ, Wu JY, Chen YT, Gau SS.

Mol Autism. 2016 Apr 1;7:23. doi: 10.1186/s13229-016-0087-7. eCollection 2016.

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