Format
Sort by
Items per page

Send to

Choose Destination

Links from Gene

Items: 1 to 20 of 44

1.

CTRC gene polymorphism (p.G60=; c.180 C > T) in acute pancreatitis.

Koziel D, Gluszek S, Kowalik A, Chlopek M.

BMC Gastroenterol. 2017 Jan 17;17(1):13. doi: 10.1186/s12876-016-0566-5.

2.

Report of 2 CTRC Intronic Mutations Associated With Acute or Chronic Pancreatitis and Delineation of Their Pathogenic Molecular Mechanisms.

Masson E, Chen JM, Férec C.

Pancreas. 2015 Aug;44(6):999-1001. doi: 10.1097/MPA.0000000000000359. No abstract available.

PMID:
26166474
3.

Mesotrypsin Signature Mutation in a Chymotrypsin C (CTRC) Variant Associated with Chronic Pancreatitis.

Szabó A, Ludwig M, Hegyi E, Szépeová R, Witt H, Sahin-Tóth M.

J Biol Chem. 2015 Jul 10;290(28):17282-92. doi: 10.1074/jbc.M114.618439. Epub 2015 May 26.

4.

Long-range electrostatic complementarity governs substrate recognition by human chymotrypsin C, a key regulator of digestive enzyme activation.

Batra J, Szabó A, Caulfield TR, Soares AS, Sahin-Tóth M, Radisky ES.

J Biol Chem. 2013 Apr 5;288(14):9848-59. doi: 10.1074/jbc.M113.457382. Epub 2013 Feb 19.

5.

Identification of novel missense CTRC variants in Japanese patients with chronic pancreatitis.

Masamune A, Nakano E, Kume K, Kakuta Y, Ariga H, Shimosegawa T.

Gut. 2013 Apr;62(4):653-4. doi: 10.1136/gutjnl-2012-303860. Epub 2012 Nov 7. No abstract available.

PMID:
23135764
6.

Comprehensive functional analysis of chymotrypsin C (CTRC) variants reveals distinct loss-of-function mechanisms associated with pancreatitis risk.

Beer S, Zhou J, Szabó A, Keiles S, Chandak GR, Witt H, Sahin-Tóth M.

Gut. 2013 Nov;62(11):1616-24. doi: 10.1136/gutjnl-2012-303090. Epub 2012 Sep 1.

7.

Comprehensive screening of chymotrypsin C (CTRC) gene in tropical calcific pancreatitis identifies novel variants.

Paliwal S, Bhaskar S, Mani KR, Reddy DN, Rao GV, Singh SP, Thomas V, Chandak GR.

Gut. 2013 Nov;62(11):1602-6. doi: 10.1136/gutjnl-2012-302448. Epub 2012 May 12.

PMID:
22580415
8.

Chymotrypsin C mutations in chronic pancreatitis.

Zhou J, Sahin-Tóth M.

J Gastroenterol Hepatol. 2011 Aug;26(8):1238-46. doi: 10.1111/j.1440-1746.2011.06791.x. Review.

9.

Association of novel chymotrypsin C gene variations and haplotypes in patients with chronic pancreatitis in Chinese in Taiwan.

Chang MC, Chang YT, Wei SC, Liang PC, Jan IS, Su YN, Kuo CH, Wong JM.

Pancreatology. 2009;9(3):287-92. doi: 10.1159/000199437. Epub 2009 Apr 29.

PMID:
19407484
10.

Association of rare chymotrypsinogen C (CTRC) gene variations in patients with idiopathic chronic pancreatitis.

Masson E, Chen JM, Scotet V, Le Maréchal C, Férec C.

Hum Genet. 2008 Feb;123(1):83-91. doi: 10.1007/s00439-007-0459-3. Epub 2008 Jan 3.

PMID:
18172691
11.

Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis.

Rosendahl J, Witt H, Szmola R, Bhatia E, Ozsvári B, Landt O, Schulz HU, Gress TM, Pfützer R, Löhr M, Kovacs P, Blüher M, Stumvoll M, Choudhuri G, Hegyi P, te Morsche RH, Drenth JP, Truninger K, Macek M Jr, Puhl G, Witt U, Schmidt H, Büning C, Ockenga J, Kage A, Groneberg DA, Nickel R, Berg T, Wiedenmann B, Bödeker H, Keim V, Mössner J, Teich N, Sahin-Tóth M.

Nat Genet. 2008 Jan;40(1):78-82. Epub 2007 Dec 2.

12.

Chymotrypsin C (caldecrin) promotes degradation of human cationic trypsin: identity with Rinderknecht's enzyme Y.

Szmola R, Sahin-Tóth M.

Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11227-32. Epub 2007 Jun 25.

13.

Molecular cloning and expression of human caldecrin.

Tomomura A, Akiyama M, Itoh H, Yoshino I, Tomomura M, Nishii Y, Noikura T, Saheki T.

FEBS Lett. 1996 May 13;386(1):26-8.

14.

Early-Onset Acute Recurrent and Chronic Pancreatitis Is Associated with PRSS1 or CTRC Gene Mutations.

Giefer MJ, Lowe ME, Werlin SL, Zimmerman B, Wilschanski M, Troendle D, Schwarzenberg SJ, Pohl JF, Palermo J, Ooi CY, Morinville VD, Lin TK, Husain SZ, Himes R, Heyman MB, Gonska T, Gariepy CE, Freedman SD, Fishman DS, Bellin MD, Barth B, Abu-El-Haija M, Uc A.

J Pediatr. 2017 Jul;186:95-100. doi: 10.1016/j.jpeds.2017.03.063. Epub 2017 May 10.

PMID:
28502372
15.

Tighter Control by Chymotrypsin C (CTRC) Explains Lack of Association between Human Anionic Trypsinogen and Hereditary Pancreatitis.

Jancsó Z, Sahin-Tóth M.

J Biol Chem. 2016 Jun 17;291(25):12897-905. doi: 10.1074/jbc.M116.725374. Epub 2016 Apr 18.

16.

ER stress-associated CTRC mutants decrease stimulated pancreatic zymogen secretion through SIRT2-mediated microtubule dysregulation.

Binker MG, Richards D, Gaisano HY, Cosen-Binker LI.

Biochem Biophys Res Commun. 2015 Jul 31;463(3):329-35. doi: 10.1016/j.bbrc.2015.05.064. Epub 2015 May 28.

PMID:
26022124
17.

Increased activation of hereditary pancreatitis-associated human cationic trypsinogen mutants in presence of chymotrypsin C.

Szabó A, Sahin-Tóth M.

J Biol Chem. 2012 Jun 8;287(24):20701-10. doi: 10.1074/jbc.M112.360065. Epub 2012 Apr 26.

18.

Effect of chymotrypsin C and related proteins on pancreatic cancer cell migration.

Wang H, Sha W, Liu Z, Chi CW.

Acta Biochim Biophys Sin (Shanghai). 2011 May;43(5):362-71. doi: 10.1093/abbs/gmr022. Epub 2011 Apr 2.

PMID:
21460362
19.

Tropical calcific pancreatitis and its association with CTRC and SPINK1 (p.N34S) variants.

Derikx MH, Szmola R, te Morsche RH, Sunderasan S, Chacko A, Drenth JP.

Eur J Gastroenterol Hepatol. 2009 Aug;21(8):889-94. doi: 10.1097/MEG.0b013e32832183cf.

PMID:
19404200
20.

Acetaldehyde inhibits chymotrypsin and serum anti-chymotrypsin activity.

Brecher AS, Yang MP.

J Investig Med. 1998 Apr;46(4):146-52.

PMID:
9635374

Supplemental Content

Support Center