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HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients with inherited primary arrhythmia syndromes: document endorsed by HRS, EHRA, and APHRS in May 2013 and by ACCF, AHA, PACES, and AEPC in June 2013.

Priori SG, Wilde AA, Horie M, Cho Y, Behr ER, Berul C, Blom N, Brugada J, Chiang CE, Huikuri H, Kannankeril P, Krahn A, Leenhardt A, Moss A, Schwartz PJ, Shimizu W, Tomaselli G, Tracy C.

Heart Rhythm. 2013 Dec;10(12):1932-63. doi: 10.1016/j.hrthm.2013.05.014. Epub 2013 Aug 30. Review. No abstract available.


Competitive sports participation in athletes with congenital long QT syndrome.

Johnson JN, Ackerman MJ.

JAMA. 2012 Aug 22;308(8):764-5. doi: 10.1001/jama.2012.9334. No abstract available.


Mortality of inherited arrhythmia syndromes: insight into their natural history.

Nannenberg EA, Sijbrands EJ, Dijksman LM, Alders M, van Tintelen JP, Birnie M, van Langen IM, Wilde AA.

Circ Cardiovasc Genet. 2012 Apr 1;5(2):183-9. doi: 10.1161/CIRCGENETICS.111.961102. Epub 2012 Feb 28.


QTc behavior during exercise and genetic testing for the long-QT syndrome.

Schwartz PJ, Crotti L.

Circulation. 2011 Nov 15;124(20):2181-4. doi: 10.1161/CIRCULATIONAHA.111.062182. No abstract available.


Derivation and validation of a simple exercise-based algorithm for prediction of genetic testing in relatives of LQTS probands.

Sy RW, van der Werf C, Chattha IS, Chockalingam P, Adler A, Healey JS, Perrin M, Gollob MH, Skanes AC, Yee R, Gula LJ, Leong-Sit P, Viskin S, Klein GJ, Wilde AA, Krahn AD.

Circulation. 2011 Nov 15;124(20):2187-94. doi: 10.1161/CIRCULATIONAHA.111.028258. Epub 2011 Oct 31.


HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies this document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA).

Ackerman MJ, Priori SG, Willems S, Berul C, Brugada R, Calkins H, Camm AJ, Ellinor PT, Gollob M, Hamilton R, Hershberger RE, Judge DP, Le Marec H, McKenna WJ, Schulze-Bahr E, Semsarian C, Towbin JA, Watkins H, Wilde A, Wolpert C, Zipes DP.

Heart Rhythm. 2011 Aug;8(8):1308-39. doi: 10.1016/j.hrthm.2011.05.020. No abstract available.


The diagnostic utility of recovery phase QTc during treadmill exercise stress testing in the evaluation of long QT syndrome.

Horner JM, Horner MM, Ackerman MJ.

Heart Rhythm. 2011 Nov;8(11):1698-704. doi: 10.1016/j.hrthm.2011.05.018. Epub 2011 May 30.


Risk for life-threatening cardiac events in patients with genotype-confirmed long-QT syndrome and normal-range corrected QT intervals.

Goldenberg I, Horr S, Moss AJ, Lopes CM, Barsheshet A, McNitt S, Zareba W, Andrews ML, Robinson JL, Locati EH, Ackerman MJ, Benhorin J, Kaufman ES, Napolitano C, Platonov PG, Priori SG, Qi M, Schwartz PJ, Shimizu W, Towbin JA, Vincent GM, Wilde AA, Zhang L.

J Am Coll Cardiol. 2011 Jan 4;57(1):51-9. doi: 10.1016/j.jacc.2010.07.038.


Screening for copy number variation in genes associated with the long QT syndrome: clinical relevance.

Barc J, Briec F, Schmitt S, Kyndt F, Le Cunff M, Baron E, Vieyres C, Sacher F, Redon R, Le Caignec C, Le Marec H, Probst V, Schott JJ.

J Am Coll Cardiol. 2011 Jan 4;57(1):40-7. doi: 10.1016/j.jacc.2010.08.621.


Long QT syndrome with compound mutations is associated with a more severe phenotype: a Japanese multicenter study.

Itoh H, Shimizu W, Hayashi K, Yamagata K, Sakaguchi T, Ohno S, Makiyama T, Akao M, Ai T, Noda T, Miyazaki A, Miyamoto Y, Yamagishi M, Kamakura S, Horie M.

Heart Rhythm. 2010 Oct;7(10):1411-8. doi: 10.1016/j.hrthm.2010.06.013. Epub 2010 Jun 9.


Risk of fatal arrhythmic events in long QT syndrome patients after syncope.

Jons C, Moss AJ, Goldenberg I, Liu J, McNitt S, Zareba W, Qi M, Robinson JL.

J Am Coll Cardiol. 2010 Feb 23;55(8):783-8. doi: 10.1016/j.jacc.2009.11.042.


The response of the QT interval to the brief tachycardia provoked by standing: a bedside test for diagnosing long QT syndrome.

Viskin S, Postema PG, Bhuiyan ZA, Rosso R, Kalman JM, Vohra JK, Guevara-Valdivia ME, Marquez MF, Kogan E, Belhassen B, Glikson M, Strasberg B, Antzelevitch C, Wilde AA.

J Am Coll Cardiol. 2010 May 4;55(18):1955-61. doi: 10.1016/j.jacc.2009.12.015. Epub 2010 Jan 29.


Genetic testing for long-QT syndrome: distinguishing pathogenic mutations from benign variants.

Kapa S, Tester DJ, Salisbury BA, Harris-Kerr C, Pungliya MS, Alders M, Wilde AA, Ackerman MJ.

Circulation. 2009 Nov 3;120(18):1752-60. doi: 10.1161/CIRCULATIONAHA.109.863076. Epub 2009 Oct 19.


Spectrum and prevalence of mutations from the first 2,500 consecutive unrelated patients referred for the FAMILION long QT syndrome genetic test.

Kapplinger JD, Tester DJ, Salisbury BA, Carr JL, Harris-Kerr C, Pollevick GD, Wilde AA, Ackerman MJ.

Heart Rhythm. 2009 Sep;6(9):1297-303. doi: 10.1016/j.hrthm.2009.05.021. Epub 2009 Jun 23.


Clinical implications for patients with long QT syndrome who experience a cardiac event during infancy.

Spazzolini C, Mullally J, Moss AJ, Schwartz PJ, McNitt S, Ouellet G, Fugate T, Goldenberg I, Jons C, Zareba W, Robinson JL, Ackerman MJ, Benhorin J, Crotti L, Kaufman ES, Locati EH, Qi M, Napolitano C, Priori SG, Towbin JA, Vincent GM.

J Am Coll Cardiol. 2009 Aug 25;54(9):832-7. doi: 10.1016/j.jacc.2009.05.029.


All LQT3 patients need an ICD: true or false?

Schwartz PJ, Spazzolini C, Crotti L.

Heart Rhythm. 2009 Jan;6(1):113-20. doi: 10.1016/j.hrthm.2008.10.017. Epub 2008 Oct 15. No abstract available.


High efficacy of beta-blockers in long-QT syndrome type 1: contribution of noncompliance and QT-prolonging drugs to the occurrence of beta-blocker treatment "failures".

Vincent GM, Schwartz PJ, Denjoy I, Swan H, Bithell C, Spazzolini C, Crotti L, Piippo K, Lupoglazoff JM, Villain E, Priori SG, Napolitano C, Zhang L.

Circulation. 2009 Jan 20;119(2):215-21. doi: 10.1161/CIRCULATIONAHA.108.772533. Epub 2008 Dec 31.


Long QT Syndrome.

Goldenberg I, Zareba W, Moss AJ.

Curr Probl Cardiol. 2008 Nov;33(11):629-94. doi: 10.1016/j.cpcardiol.2008.07.002. Review.


Ranolazine shortens repolarization in patients with sustained inward sodium current due to type-3 long-QT syndrome.

Moss AJ, Zareba W, Schwarz KQ, Rosero S, McNitt S, Robinson JL.

J Cardiovasc Electrophysiol. 2008 Dec;19(12):1289-93. doi: 10.1111/j.1540-8167.2008.01246.x. Epub 2008 Jul 25.


Risk of death in the long QT syndrome when a sibling has died.

Kaufman ES, McNitt S, Moss AJ, Zareba W, Robinson JL, Hall WJ, Ackerman MJ, Benhorin J, Locati ET, Napolitano C, Priori SG, Schwartz PJ, Towbin JA, Vincent GM, Zhang L.

Heart Rhythm. 2008 Jun;5(6):831-6. doi: 10.1016/j.hrthm.2008.02.029. Epub 2008 Mar 4.

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