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The Fanconi anemia core complex forms four complexes of different sizes in different subcellular compartments.

Thomashevski A, High AA, Drozd M, Shabanowitz J, Hunt DF, Grant PA, Kupfer GM.

J Biol Chem. 2004 Jun 18;279(25):26201-9. Epub 2004 Apr 13.


The p38 pathway partially mediates caspase-3 activation induced by reactive oxygen species in Fanconi anemia C cells.

Pearl-Yafe M, Halperin D, Scheuerman O, Fabian I.

Biochem Pharmacol. 2004 Feb 1;67(3):539-46.


Oxidant hypersensitivity of Fanconi anemia type C-deficient cells is dependent on a redox-regulated apoptotic pathway.

Saadatzadeh MR, Bijangi-Vishehsaraei K, Hong P, Bergmann H, Haneline LS.

J Biol Chem. 2004 Apr 16;279(16):16805-12. Epub 2004 Feb 5.


Fanconi's anemia cell lines show distinct mechanisms of cell death in response to mitomycin C or agonistic anti-Fas antibodies.

Clarke AA, Gibson FM, Scott J, Myatt N, Rutherford TR.

Haematologica. 2004 Jan;89(1):11-20.


Evaluation of Fanconi Anemia genes in familial breast cancer predisposition.

Seal S, Barfoot R, Jayatilake H, Smith P, Renwick A, Bascombe L, McGuffog L, Evans DG, Eccles D, Easton DF, Stratton MR, Rahman N; Breast Cancer Susceptibility Collaboration.

Cancer Res. 2003 Dec 15;63(24):8596-9.


Regulation of the Fanconi anemia group C protein through proteolytic modification.

Brodeur I, Goulet I, Tremblay CS, Charbonneau C, Delisle MC, Godin C, Huard C, Khandjian EW, Buchwald M, Lévesque G, Carreau M.

J Biol Chem. 2004 Feb 6;279(6):4713-20. Epub 2003 Nov 18.


A novel ubiquitin ligase is deficient in Fanconi anemia.

Meetei AR, de Winter JP, Medhurst AL, Wallisch M, Waisfisz Q, van de Vrugt HJ, Oostra AB, Yan Z, Ling C, Bishop CE, Hoatlin ME, Joenje H, Wang W.

Nat Genet. 2003 Oct;35(2):165-70. Epub 2003 Sep 14.


Fanconi anemia type C and p53 cooperate in apoptosis and tumorigenesis.

Freie B, Li X, Ciccone SL, Nawa K, Cooper S, Vogelweid C, Schantz L, Haneline LS, Orazi A, Broxmeyer HE, Lee SH, Clapp DW.

Blood. 2003 Dec 1;102(12):4146-52. Epub 2003 Jul 10.


Fanconi anemia genes are highly expressed in primitive CD34+ hematopoietic cells.

Aubé M, Lafrance M, Brodeur I, Delisle MC, Carreau M.

BMC Blood Disord. 2003 Jun 16;3(1):1.


Fanconi anemia gene mutations in young-onset pancreatic cancer.

van der Heijden MS, Yeo CJ, Hruban RH, Kern SE.

Cancer Res. 2003 May 15;63(10):2585-8.


Constitutional sequence variation in the Fanconi anaemia group C (FANCC) gene in childhood acute myeloid leukaemia.

Barber LM, McGrath HE, Meyer S, Will AM, Birch JM, Eden OB, Taylor GM.

Br J Haematol. 2003 Apr;121(1):57-62.


Roles of MAPKKK ASK1 in stress-induced cell death.

Takeda K, Matsuzawa A, Nishitoh H, Ichijo H.

Cell Struct Funct. 2003 Feb;28(1):23-9. Review.


Fanconi anemia protein complex: mapping protein interactions in the yeast 2- and 3-hybrid systems.

Gordon SM, Buchwald M.

Blood. 2003 Jul 1;102(1):136-41. Epub 2003 Mar 20.


An oxidative mechanism of interferon induced priming of the Fas pathway in Fanconi anemia cells.

Pearl-Yafe M, Halperin D, Halevy A, Kalir H, Bielorai B, Fabian I.

Biochem Pharmacol. 2003 Mar 1;65(5):833-42.


In vivo administration of interferon gamma does not cause marrow aplasia in mice with a targeted disruption of FANCC.

Kurre P, Anandakumar P, Grompe M, Kiem HP.

Exp Hematol. 2002 Nov;30(11):1257-62.


Plzf mediates transcriptional repression of HoxD gene expression through chromatin remodeling.

Barna M, Merghoub T, Costoya JA, Ruggero D, Branford M, Bergia A, Samori B, Pandolfi PP.

Dev Cell. 2002 Oct;3(4):499-510.


Retroviral-mediated expression of recombinant Fancc enhances the repopulating ability of Fancc-/- hematopoietic stem cells and decreases the risk of clonal evolution.

Haneline LS, Li X, Ciccone SL, Hong P, Yang Y, Broxmeyer HE, Lee SH, Orazi A, Srour EF, Clapp DW.

Blood. 2003 Feb 15;101(4):1299-307. Epub 2002 Oct 10.


Liver protection from apoptosis requires both blockage of initiator caspase activities and inhibition of ASK1/JNK pathway via glutathione S-transferase regulation.

Gilot D, Loyer P, Corlu A, Glaise D, Lagadic-Gossmann D, Atfi A, Morel F, Ichijo H, Guguen-Guillouzo C.

J Biol Chem. 2002 Dec 20;277(51):49220-9. Epub 2002 Oct 4.

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