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AJNR Am J Neuroradiol. 1997 Sep;18(8):1541-7.

Detection of pyramidal tract lesions in amyotrophic lateral sclerosis with magnetization-transfer measurements.

Author information

1
Department of Neurology, Mie University School of Medicine, Japan.

Abstract

PURPOSE:

To determine the presence of small lesions in the pyramidal tract in patients with amyotrophic lateral sclerosis (ALS) by using magnetization-transfer (MT) measurements and MR imaging.

METHODS:

MT ratios (MTRs) were measured in the posterior limb of the internal capsule in nine patients with ALS and in nine healthy volunteers.

RESULTS:

The mean value of MTRs (%) in patients with ALS was 15.76 +/- 1.48, while that of the control subjects was 19.83 +/- 1.54. The difference was statistically significant.

CONCLUSIONS:

MT measurements are useful for detecting abnormalities associated with degeneration of the pyramidal tract in patients with ALS.

PMID:
9296197
[Indexed for MEDLINE]
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