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Anal Quant Cytol. 1979 Mar-Apr;1(1):67-76.

Use of the positive difference transform for RBC elimination in bone marrow smear images.

Abstract

The use of an algorithm with a broad range of utility in digital image processing (the positive difference transform) is illustrated. Its effectiveness as a procedure for selective elimination of hemoglobin-containing images is demonstrated. A set of heuristics, employing information concerning nuclear hemoglobin content, is shown to discriminate nucleated erythrocytic cells from those of the leukocyte series.

PMID:
546280
[Indexed for MEDLINE]

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