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Open Forum Infect Dis. 2017 Jul 22;4(3):ofx155. doi: 10.1093/ofid/ofx155. eCollection 2017 Summer.

Ebola Virus Ribonucleic Acid Detection in Semen More Than Two Years After Resolution of Acute Ebola Virus Infection.

Author information

1
Divisions of Pulmonary and Critical Care Medicine and.
2
Eternal Love Winning Africa Hospital, Monrovia, Liberia.
3
Infectious Disease and.
4
Phebe Hospital & School of Nursing, Suakoko, Bong County, Liberia.
5
Department of Pediatrics, Duke University Medical Center, Durham, North Carolina.
6
Public Health Leadership Program, The University of North Carolina at Chapel Hill.
7
Clinical Research Management, Inc. (ClinicalRM), Hinckley, Ohio; and.
8
Ebola Survivor Association of Liberia Inc, Monrovia.

Abstract

Among 149 men who survived Ebola virus disease (EVD) and donated semen 260-1016 days after EVD onset, Ebola virus (EBOV) ribonucleic acid (RNA) was detected in 13 (9%). Of 137 men who donated semen 2 years after EVD onset, 11 (8%) had an EBOV RNA-positive specimen. The mechanism underlying the persistence of EBOV RNA in semen is unclear, and it is unclear whether the detection of viral RNA represents the presence of infectious virus.

KEYWORDS:

Ebola; PCR; semen; viral persistence

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