Format

Send to

Choose Destination
J Virol. 2016 Sep 12;90(19):8389-94. doi: 10.1128/JVI.00041-16. Print 2016 Oct 1.

To Conquer the Host, Influenza Virus Is Packing It In: Interferon-Antagonistic Strategies beyond NS1.

Author information

1
Laboratory of Molecular Genetics, Institute for Virus Research, Kyoto University, Kyoto, Japan.
2
Institute for Virology, FB10-Veterinary Medicine, Justus Liebig University, Giessen, Germany friedemann.weber@vetmed.uni-giessen.de.

Abstract

The nonstructural protein NS1 is well established as a virulence factor of influenza A virus counteracting induction of the antiviral type I interferon system. Recent studies now show that viral structural proteins, their derivatives, and even the genome itself also contribute to keeping the host defense under control. Here, we summarize the current knowledge on these NS1-independent interferon escape strategies.

PMID:
27440898
PMCID:
PMC5021431
DOI:
10.1128/JVI.00041-16
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for PubMed Central
Loading ...
Support Center