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Neurophysiol Clin. 2016 Apr;46(2):125-33. doi: 10.1016/j.neucli.2016.05.001. Epub 2016 May 24.

The value of preoperative functional cortical mapping using navigated TMS.

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EA 4391, faculté de médecine de Créteil, université Paris Est Créteil, 94000 Créteil, France; Service de physiologie-explorations fonctionnelles, hôpital Henri-Mondor, Assistance publique-Hôpitaux de Paris, 94010 Créteil, France. Electronic address:
Department of Neurosurgery, Charité University Hospital, Berlin, Germany.


The surgical removal of brain tumours in so-called eloquent regions is frequently associated with a high risk of causing disabling postoperative deficits. Among the preoperative techniques proposed to help neurosurgical planning and procedure, navigated transcranial magnetic stimulation (nTMS) is increasingly performed. A high level of evidence is now available in the literature regarding the anatomical and functional accuracy of this mapping technique. This article presents the principles and facts demonstrating the value of using nTMS in clinical practice to preserve motor or language functions from deleterious lesions secondary to brain tumour resection or epilepsy surgery.


Aire de Broca; Brain tumour; Broca's area; Cortex moteur; Langage; Language; Motor cortex; Neurochirurgie; Neuronavigation; Neurosurgery; Parole; Speech; Stimulation magnétique transcrânienne; Transcranial magnetic stimulation; Tumeur cérébrale

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