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Database (Oxford). 2015 Dec 26;2015. pii: bav115. doi: 10.1093/database/bav115. Print 2015.

LymPHOS 2.0: an update of a phosphosite database of primary human T cells.

Author information

1
CSIC/UAB Proteomics Laboratory, Instituto De Investigaciones Biomédicas De Barcelona-Consejo Superior De Investigaciones Científicas (IIBB-CSIC/IDIBAPS), Rosellón 161 6a Planta, Barcelona E-08036, Spain.
2
CSIC/UAB Proteomics Laboratory, Instituto De Investigaciones Biomédicas De Barcelona-Consejo Superior De Investigaciones Científicas (IIBB-CSIC/IDIBAPS), Rosellón 161 6a Planta, Barcelona E-08036, Spain montserrat.carrascal.csic@uab.cat.

Abstract

LymPHOS is a web-oriented database containing peptide and protein sequences and spectrometric information on the phosphoproteome of primary human T-Lymphocytes. Current release 2.0 contains 15 566 phosphorylation sites from 8273 unique phosphopeptides and 4937 proteins, which correspond to a 45-fold increase over the original database description. It now includes quantitative data on phosphorylation changes after time-dependent treatment with activators of the TCR-mediated signal transduction pathway. Sequence data quality has also been improved with the use of multiple search engines for database searching. LymPHOS can be publicly accessed at http://www.lymphos.org. Database URL: http://www.lymphos.org.

PMID:
26708986
PMCID:
PMC4691341
DOI:
10.1093/database/bav115
[Indexed for MEDLINE]
Free PMC Article

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