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PLoS One. 2015 May 26;10(5):e0126559. doi: 10.1371/journal.pone.0126559. eCollection 2015.

Smartphone-Supported versus Full Behavioural Activation for Depression: A Randomised Controlled Trial.

Author information

1
Department of Behavioural Sciences and Learning, Linköping University, Linköping, Sweden.
2
Department of Psychology, Stockholm University, Stockholm, Sweden.
3
Wemind Psykiatri Stockholm, Stockholm, Sweden.
4
Department of Behavioural Sciences and Learning, Linköping University, Linköping, Sweden; Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institute, Stockholm, Sweden.

Abstract

BACKGROUND:

There is need for more cost and time effective treatments for depression. This is the first randomised controlled trial in which a blended treatment--including four face-to-face sessions and a smartphone application--was compared against a full behavioural treatment. Hence, the aim of the current paper was to examine whether a blended smartphone treatment was non-inferior to a full behavioural activation treatment for depression.

METHODS:

This was a randomised controlled non-inferiority trial (NCT01819025) comparing a blended treatment (n=46) against a full ten-session treatment (n=47) for people suffering from major depression. Primary outcome measure was the BDI-II, that was administered at pre- and post-treatment, as well as six months after the treatment.

RESULTS:

Results showed significant improvements in both groups across time on the primary outcome measure (within-group Cohen's d=1.35; CI [-0.82, 3.52] to d=1.47; CI [-0.41, 3.35]; between group d=-0.13 CI [-2.37, 2.09] and d=-0.10 CI [-2.53, 2.33]). At the same time, the blended treatment reduced the therapist time with an average of 47%.

CONCLUSIONS:

We could not establish whether the blended treatment was non-inferior to a full BA treatment. Nevertheless, this study points to that the blended treatment approach could possibly treat nearly twice as many patients suffering from depression by using a smartphone application as add-on. More studies are needed before we can suggest that the blended treatment method is a promising cost-effective alternative to regular face-to-face treatment for depression.

TRIAL REGISTRATION:

Cognitive Behavioral Therapy Treatment of Depression With Smartphone Support NCT01819025.

PMID:
26010890
PMCID:
PMC4444307
DOI:
10.1371/journal.pone.0126559
[Indexed for MEDLINE]
Free PMC Article

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