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Infect Dis Clin North Am. 2015 Jun;29(2):325-40. doi: 10.1016/j.idc.2015.02.006.

Chronic Lyme disease.

Author information

1
Divisions of Pediatric Infectious Diseases and General Internal Medicine, Duke University School of Medicine, DUMC 100800, Durham, NC 27710, USA. Electronic address: paul.lantos@duke.edu.

Abstract

Chronic Lyme disease is a poorly defined diagnosis that is usually given to patients with prolonged, unexplained symptoms or with alternative medical diagnoses. Data do not support the proposition that chronic, treatment-refractory infection with Borrelia burgdorferi is responsible for the many conditions that get labeled as chronic Lyme disease. Prolonged symptoms after successful treatment of Lyme disease are uncommon, but in rare cases may be severe. Prolonged courses of antibiotics neither prevent nor ameliorate these symptoms and are associated with considerable harm.

KEYWORDS:

Antibiotics; Borrelia burgdorferi; Chronic Lyme disease; Chronic fatigue; Chronic pain; Lyme disease

PMID:
25999227
PMCID:
PMC4477530
DOI:
10.1016/j.idc.2015.02.006
[Indexed for MEDLINE]
Free PMC Article

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