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Antimicrob Agents Chemother. 1985 Sep;28(3):437-9.

Antibacterial activities of antineoplastic agents.

Abstract

Fourteen antineoplastic agents were examined for in vitro antibacterial activity against 101 aerobic and anaerobic bacterial isolates representing indigenous human microflora and selected opportunistic pathogens. Only 5-fluorouracil, mitomycin, and etoposide demonstrated inhibitory effects at achievable plasma concentrations, while the remaining drugs lacked appreciable antibacterial activities.

PMID:
2416271
PMCID:
PMC180269
DOI:
10.1128/aac.28.3.437
[Indexed for MEDLINE]
Free PMC Article

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