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Nat Neurosci. 2013 Sep;16(9):1188-90. doi: 10.1038/nn.3466. Epub 2013 Aug 4.

Direct recordings of grid-like neuronal activity in human spatial navigation.

Author information

1
School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, Pennsylvania, USA. joshua.jacobs@drexel.edu

Abstract

Grid cells in the entorhinal cortex appear to represent spatial location via a triangular coordinate system. Such cells, which have been identified in rats, bats and monkeys, are believed to support a wide range of spatial behaviors. Recording neuronal activity from neurosurgical patients performing a virtual-navigation task, we identified cells exhibiting grid-like spiking patterns in the human brain, suggesting that humans and simpler animals rely on homologous spatial-coding schemes.

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PMID:
23912946
PMCID:
PMC3767317
DOI:
10.1038/nn.3466
[Indexed for MEDLINE]
Free PMC Article

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