Format

Send to

Choose Destination
Clin Neurophysiol. 2014 Jan;125(1):83-97. doi: 10.1016/j.clinph.2013.06.015. Epub 2013 Jul 16.

Group Independent Component Analysis (gICA) and Current Source Density (CSD) in the study of EEG in ADHD adults.

Author information

1
N.P. Bechtereva Institute of the Human Brain of Russian Academy of Sciences, St. Petersburg, Russia. Electronic address: valery_ponomarev@mail.ru.
2
Brain and Trauma Foundation Grisons, Chur, Switzerland.
3
N.P. Bechtereva Institute of the Human Brain of Russian Academy of Sciences, St. Petersburg, Russia.

Abstract

OBJECTIVE:

To investigate the performance of the spectral analysis of resting EEG, Current Source Density (CSD) and group independent components (gIC) in diagnosing ADHD adults.

METHODS:

Power spectra of resting EEG, CSD and gIC (19 channels, linked ears reference, eyes open/closed) from 96 ADHD and 376 healthy adults were compared between eyes open and eyes closed conditions, and between groups of subjects.

RESULTS:

Pattern of differences in gIC and CSD spectral power between conditions was approximately similar, whereas it was more widely spatially distributed for EEG. Size effect (Cohen's d) of differences in gIC and CSD spectral power between groups of subjects was considerably greater than in the case of EEG. Significant reduction of gIC and CSD spectral power depending on conditions was found in ADHD patients. Reducing power in a wide frequency range in the fronto-central areas is a common phenomenon regardless of whether the eyes were open or closed.

CONCLUSIONS:

Spectral power of local EEG activity isolated by gICA or CSD in the fronto-central areas may be a suitable marker for discrimination of ADHD and healthy adults.

SIGNIFICANCE:

Spectral analysis of gIC and CSD provides better sensitivity to discriminate ADHD and healthy adults.

KEYWORDS:

ADHD; Current Source Density; EEG spectra; Group Independent Component Analysis

PMID:
23871197
DOI:
10.1016/j.clinph.2013.06.015
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center