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Neoplasma. 1990;37(3):343-8.

Antimetastatic action of diltiazem on LS/BL tumor cells in liver tumor-colony assay.

Author information

1
Institute of Biophysics, Czechoslovak Academy of Sciences, Brno.

Abstract

Inhibition of experimental metastases of lymphosarcoma LS/BL cells by diltiazem, a calcium blocking agent, was tested. Diltiazem treatment (2 X 30 mg/kg p.o. for 12 days) resulted in a maximum of 72.8% inhibition of liver metastases. The authors suggest that diltiazem might become suitable candidate for antimetastatic treatment in humans.

PMID:
2370918
[Indexed for MEDLINE]

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