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Clin Lab Med. 2010 Mar;30(1):179-208. doi: 10.1016/j.cll.2010.01.005.

Staphylococcus aureus: An old pathogen with new weapons.

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Department of Pathology and Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA. <>


Staphylococcus aureus has been recognized as an important human pathogen for more than 100 years. S aureus has been able to adapt and evolve in terms of its resistance traits and virulence factors; it is among the most important causes of human infections in the twenty-first century. Rapid molecular identification in the clinical microbiology laboratory of these resistance and virulence factors expressed by S aureus will play an important role in the future in decreasing the morbidity and mortality of infections. This article addresses the emerging aspects of infections caused by S aureus, including microbiology, epidemiology, clinical presentation, pathogenesis, diagnosis, treatment and prognosis, and immunity.

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