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Immunity. 2010 Mar 26;32(3):300-2. doi: 10.1016/j.immuni.2010.03.010.

Interleukin-18 in intestinal inflammation: friend and foe?

Author information

1
Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Medizinische Klinik I, Hindenburgdamm 30, Berlin, Germany. britta.siegmund@charite.de

Abstract

Genetic studies and other experimental data have linked inflammatory bowel diseases with inflammasome activation. In this issue of Immunity, Zaki et al. (2010) and Dupaul-Chicoine et al. (2010) provide a detailed characterization of the regulatory task of the inflammasome in intestinal epithelial cells.

PMID:
20346770
DOI:
10.1016/j.immuni.2010.03.010
[Indexed for MEDLINE]
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