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Immunity. 2009 Dec 18;31(6):849-51. doi: 10.1016/j.immuni.2009.12.002.

The multiple mechanisms of T cell receptor cross-reactivity.

Author information

1
Center for Advanced Research in Biotechnology, WM Keck Laboratory for Structural Biology, University of Maryland Biotechnology Institute, Rockville, Maryland 20850, USA.

Abstract

The ability of a single T cell to recognize the diverse peptides it encounters is based on T cell receptor crossreactivity. In this issue of Immunity, Macdonald et al. (2009) and Borbulevych et al. (2009) provide new insights into the structural principles underlying this fundamental property of T cells.

PMID:
20064442
DOI:
10.1016/j.immuni.2009.12.002
[Indexed for MEDLINE]
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