Format

Send to

Choose Destination
Clin Exp Allergy. 2009 Apr;39(4):500-8. doi: 10.1111/j.1365-2222.2009.03200.x. Epub 2009 Feb 16.

Disturbed cognitive functions after nasal provocation in patients with seasonal allergic rhinitis.

Author information

1
Department of Otorhinolaryngology, Head and Neck Surgery, Faculty of Health, Medicine and Life Sciences, University Hospital Maastricht, Maastricht University, Maastricht, The Netherlands. isabelle.hartgerink@mumc.nl

Abstract

BACKGROUND:

Allergic rhinitis (AR) reduces quality of life as a result of impaired psychological well-being and perceived impaired cognitive functioning. Few studies have measured cognitive functions objectively and it remains uncertain whether AR leads to an objective reduction in cognitive functions.

OBJECTIVE:

The present study investigated whether AR is associated with a decrement in several aspects of cognitive functioning. Furthermore, the study investigated whether AR patients invest more 'mental effort' in order to achieve the same cognitive performances as healthy controls.

METHODS:

Twenty five patients with seasonal allergic rhinitis (SAR) and 26 healthy controls, matched for age, education and sex, were tested on a battery of time-demanding and strenuous objective cognitive tests and subjective questionnaires, both before and after nasal provocation (NP). The cognitive functions assessed were sustained attention, short- and long-term memory and speed of information processing. Mental effort was assessed using visual rating scales.

RESULTS:

Sustained but not short cognitive performance was impaired in patients after NP. Patients showed an increased effort on short cognitive tests.

CONCLUSION:

SAR patients suffer from cognitive performance decrements that can be compensated by additional mental effort for short tasks only.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center