Format

Send to

Choose Destination
Molecules. 2008 Apr 27;13(4):986-94.

Fluorinated analogs of malachite green: synthesis and toxicity.

Author information

1
Iowa State University Department of Chemistry, Ames, IA 50011, USA. gakraus@iastate.edu

Abstract

A series of fluorinated analogs of malachite green (MG) have been synthesized and their toxicity to Saccharomyces cerevisiae and a human ovarian epithelial cell line examined. The toxicity profiles were found to be different for these two species. Two analogs, one with 2,4-difluoro substitution and the other with 2-fluoro substitution seem to be the most promising analogs because they showed the lowest toxicity to the human cells.

PMID:
18463600
PMCID:
PMC6245195
DOI:
10.3390/molecules13040986
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Multidisciplinary Digital Publishing Institute (MDPI) Icon for PubMed Central
Loading ...
Support Center