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Psychol Bull. 2007 Nov;133(6):976-1006.

Anorexia nervosa and autism spectrum disorders: guided investigation of social cognitive endophenotypes.

Author information

1
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA. zucke001@mc.duke.edu

Abstract

Death by suicide occurs in a disproportionate percentage of individuals with anorexia nervosa (AN), with a standardized mortality ratio indicating a 57-fold greater risk of death from suicide relative to an age-matched cohort. Longitudinal studies indicate impaired social functioning increases risk for fatal outcomes, while social impairment persists following recovery. Study of social cognition in AN may elucidate impaired processes that may influence therapeutic efficacy. Symptoms of autism spectrum disorders (ASD) are overrepresented in those who evidence a chronic course. Relative to that in AN, social information processing in ASD is well characterized and may inform systematic study in AN. This article (a) reviews impaired interpersonal processes in AN, (b) compares the phenotype of AN with that of ASD,

PMID:
17967091
DOI:
10.1037/0033-2909.133.6.976
[Indexed for MEDLINE]

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