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J Cosmet Dermatol. 2007 Sep;6(3):159-62.

Hyaluronidase offers an efficacious treatment for inaesthetic hyaluronic acid overcorrection.

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Paris-Université Laser Skin Clinic, Paris, France.

Erratum in

  • J Cosmet Dermatol. 2007 Dec;6(4):298.



Hyaluronic acid is generally accepted today as the "gold standard" filler agent, and its use has subsequently grown enormously. In addition, newer facial volume augmentation indications are constantly evolving. Rare adverse events, such as granulomas, have been described. However, complications are more commonly due to product misplacement or overcorrection leading to unsightly lumps and masses. Hyaluronidase treatment of these latter adverse effects can be both effective and rapid.


This paper aims to confirm the efficacy of hyaluronidase injections in dissolving unsightly hyaluronic acid overcorrection.


A case of hyaluronic acid overcorrection is described with evaluation of the effects of hyaluronidase.


The use of hyaluronidase, injected intracutaneously permits the elimination of patient discomfort and inaesthetic lumps within a few hours.


Hyaluronidase is highly effective in eliminating HA volume overcorrection.

[Indexed for MEDLINE]

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