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J Am Acad Orthop Surg. 2006;14(10 Spec No.):S198-204.

Horizons in prosthesis development for the restoration of limb function.

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Department of Orthopaedics, Brown University, Providence, RI, USA.


The focus of our research program is the restoration of limb function through a biohybrid approach. We consider the limb conceptually as a biohybrid organ consisting of biological tissue, endoprostheses (including neural devices and joint replacements), and exoprostheses. The biohybrid limb maximizes biological function and functional articulations with optimized human-prosthesis interfaces. Our long-term goals are to create biomimetic prostheses, optimized control systems for prostheses, and optimized human-prosthesis interfaces using both limb lengthening and osseointegration techniques.

[Indexed for MEDLINE]

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