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Arch Pharm (Weinheim). 2006 Sep;339(9):527-30.

Chromium(III) complexes of D-glucosaminic acid and their effect on decreasing blood sugar in vivo.

Author information

1
Coordination Chemistry Institute, The State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, China.

Abstract

Two chromium(III) complexes of glucosaminic acid were synthesized by neutralization and exchange reaction. The formation of 1 : 1 and 2 : 3 (Cr : glucosaminate) complexes was confirmed by elemental analyses and spectroscopic studies. The effect of the complexes on decreasing blood sugar was investigated on type-2 diabetes model rats induced by tetraoxypyrimidine. The results indicated that the effect on decreasing blood sugar was comparable to that of picolinate chromium complex (Cr(pic)(3)) currently used world wide.

PMID:
16941731
DOI:
10.1002/ardp.200600053
[Indexed for MEDLINE]

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