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Trends Genet. 2006 Oct;22(10):537-44. Epub 2006 Aug 24.

Genetic architecture of the dog: sexual size dimorphism and functional morphology.

Author information

1
Department of Biology, University of Utah, Salt Lake City, UT 84112-0840, USA. lark@bioscience.utah.edu

Erratum in

  • Trends Genet. 2007 Jan;23(1):25.

Abstract

Purebred dogs are a valuable resource for genetic analysis of quantitative traits. Quantitative traits are complex, controlled by many genes that are contained within regions of the genome known as quantitative trait loci (QTL). The genetic architecture of quantitative traits is defined by the characteristics of these genes: their number, the magnitude of their effects, their positions in the genome and their interactions with each other. QTL analysis is a valuable tool for exploring genetic architecture, and highlighting regions of the genome that contribute to the variation of a trait within a population.

PMID:
16934357
PMCID:
PMC2785546
DOI:
10.1016/j.tig.2006.08.009
[Indexed for MEDLINE]
Free PMC Article

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