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J Cosmet Laser Ther. 2005 Dec;7(3-4):171-6.

Adverse reactions to dermal fillers: a review of European experiences.

Author information

1
pandre2@noos.fr

Abstract

BACKGROUND:

In Europe, numerous dermal fillers have been utilized for the past decade. A lot of drawbacks have been reported and sometimes, severe complications occurred.

OBJECTIVE:

Our purpose is to report the clinical aspects of the adverse reactions following injections of some of the dermal fillers. Histological aspects of complications are also described.

RESULTS:

Adverse reactions secondary to biodegradable products are usually time limited, but with the non-biodegradable products, we have observed severe, persistent, and recurrent complications. Histological examinations, in cases of non-biodegradable products, may show the presence and persistence of the filler.

CONCLUSION:

For the moment, there is no ideal dermal filler. All fillers can lead to adverse events and we need to inform patients fully before injecting. Clinical studies with long-term follow-up before launching a new product on the market are recommended. We believe that in Europe, at present, the CE mark is not a guarantee of safety of dermal fillers.

PMID:
16414905
DOI:
10.1080/14764170500344393
[Indexed for MEDLINE]

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