J Nat Prod. 2001 Aug;64(8):1015-8.

Phomoxanthones A and B, novel xanthone dimers from the endophytic fungus Phomopsis species.

Isaka M¹, Jaturapat A, Rukseree K, Danwisetkanjana K, Tanticharoen M, Thebtaranonth Y.

Author information

1: National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency, Rama 6 Road, Bangkok 10400, Thailand. isaka@biotec.or.th

Abstract

Phomoxanthones A (1) and B (2), two novel xanthone dimers, were isolated from the endophytic fungus Phomopsis sp. BCC 1323. Structures of 1 and 2 were elucidated by spectroscopic methods. These compounds exhibited significant in vitro antimalarial and antitubercular activities and cytotoxicity.