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Items: 1 to 20 of 52


Improving Immunotherapy Through Glycodesign.

Buettner MJ, Shah SR, Saeui CT, Ariss R, Yarema KJ.

Front Immunol. 2018 Nov 2;9:2485. doi: 10.3389/fimmu.2018.02485. eCollection 2018. Review.


Combining Butyrated ManNAc with Glycoengineered CHO Cells Improves EPO Glycan Quality and Production.

Wang Q, Chung CY, Yang W, Yang G, Chough S, Chen Y, Yin B, Bhattacharya R, Hu Y, Saeui CT, Yarema KJ, Betenbaugh MJ, Zhang H.

Biotechnol J. 2019 Apr;14(4):e1800186. doi: 10.1002/biot.201800186. Epub 2018 Oct 8.


Integration of genetic and metabolic features related to sialic acid metabolism distinguishes human breast cell subtypes.

Saeui CT, Nairn AV, Galizzi M, Douville C, Gowda P, Park M, Dharmarha V, Shah SR, Clarke A, Austin M, Moremen KW, Yarema KJ.

PLoS One. 2018 May 30;13(5):e0195812. doi: 10.1371/journal.pone.0195812. eCollection 2018.


Anisotropic biodegradable lipid coated particles for spatially dynamic protein presentation.

Meyer RA, Mathew MP, Ben-Akiva E, Sunshine JC, Shmueli RB, Ren Q, Yarema KJ, Green JJ.

Acta Biomater. 2018 May;72:228-238. doi: 10.1016/j.actbio.2018.03.056. Epub 2018 Apr 7.


Butyrated ManNAc analog improves protein expression in Chinese hamster ovary cells.

Yin B, Wang Q, Chung CY, Ren X, Bhattacharya R, Yarema KJ, Betenbaugh MJ.

Biotechnol Bioeng. 2018 Jun;115(6):1531-1541. doi: 10.1002/bit.26560. Epub 2018 Mar 14.


General and Facile Coating of Single Cells via Mild Reduction.

Kim H, Shin K, Park OK, Choi D, Kim HD, Baik S, Lee SH, Kwon SH, Yarema KJ, Hong J, Hyeon T, Hwang NS.

J Am Chem Soc. 2018 Jan 31;140(4):1199-1202. doi: 10.1021/jacs.7b08440. Epub 2018 Jan 5.


Pharmacological, Physiochemical, and Drug-Relevant Biological Properties of Short Chain Fatty Acid Hexosamine Analogues Used in Metabolic Glycoengineering.

Saeui CT, Liu L, Urias E, Morrissette-McAlmon J, Bhattacharya R, Yarema KJ.

Mol Pharm. 2018 Mar 5;15(3):705-720. doi: 10.1021/acs.molpharmaceut.7b00525. Epub 2017 Sep 13.


Determination of absolute expression profiles using multiplexed miRNA analysis.

Song Y, Kilburn D, Song JH, Cheng Y, Saeui CT, Cheung DG, Croce CM, Yarema KJ, Meltzer SJ, Liu KJ, Wang TH.

PLoS One. 2017 Jul 13;12(7):e0180988. doi: 10.1371/journal.pone.0180988. eCollection 2017.


A novel sugar analog enhances sialic acid production and biotherapeutic sialylation in CHO cells.

Yin B, Wang Q, Chung CY, Bhattacharya R, Ren X, Tang J, Yarema KJ, Betenbaugh MJ.

Biotechnol Bioeng. 2017 Aug;114(8):1899-1902. doi: 10.1002/bit.26291. Epub 2017 May 8.


Glycoengineering of Esterase Activity through Metabolic Flux-Based Modulation of Sialic Acid.

Mathew MP, Tan E, Labonte JW, Shah S, Saeui CT, Liu L, Bhattacharya R, Bovonratwet P, Gray JJ, Yarema KJ.

Chembiochem. 2017 Jul 4;18(13):1204-1215. doi: 10.1002/cbic.201600698. Epub 2017 Apr 20.


Harnessing cancer cell metabolism for theranostic applications using metabolic glycoengineering of sialic acid in breast cancer as a pioneering example.

Badr HA, AlSadek DM, El-Houseini ME, Saeui CT, Mathew MP, Yarema KJ, Ahmed H.

Biomaterials. 2017 Feb;116:158-173. doi: 10.1016/j.biomaterials.2016.11.044. Epub 2016 Nov 25. Review.


Metabolic flux-driven sialylation alters internalization, recycling, and drug sensitivity of the epidermal growth factor receptor (EGFR) in SW1990 pancreatic cancer cells.

Mathew MP, Tan E, Saeui CT, Bovonratwet P, Sklar S, Bhattacharya R, Yarema KJ.

Oncotarget. 2016 Oct 11;7(41):66491-66511. doi: 10.18632/oncotarget.11582.


Electrospun Microfiber Scaffolds with Anti-Inflammatory Tributanoylated N-Acetyl-d-Glucosamine Promote Cartilage Regeneration.

Kim C, Shores L, Guo Q, Aly A, Jeon OH, Kim DH, Bernstein N, Bhattacharya R, Chae JJ, Yarema KJ, Elisseeff JH.

Tissue Eng Part A. 2016 Apr;22(7-8):689-97. doi: 10.1089/ten.TEA.2015.0469.


Local delivery of a carbohydrate analog for reducing arthritic inflammation and rebuilding cartilage.

Kim C, Jeon OH, Kim DH, Chae JJ, Shores L, Bernstein N, Bhattacharya R, Coburn JM, Yarema KJ, Elisseeff JH.

Biomaterials. 2016 Mar;83:93-101. doi: 10.1016/j.biomaterials.2015.12.029. Epub 2015 Dec 31.


Lectin staining and Western blot data showing differential sialylation of nutrient-deprived cancer cells to sialic acid supplementation.

Badr HA, AlSadek DM, Mathew MP, Li CZ, Djansugurova LB, Yarema KJ, Ahmed H.

Data Brief. 2015 Oct 9;5:481-8. doi: 10.1016/j.dib.2015.09.043. eCollection 2015 Dec.


Nutrient-deprived cancer cells preferentially use sialic acid to maintain cell surface glycosylation.

Badr HA, AlSadek DM, Mathew MP, Li CZ, Djansugurova LB, Yarema KJ, Ahmed H.

Biomaterials. 2015 Nov;70:23-36. doi: 10.1016/j.biomaterials.2015.08.020. Epub 2015 Aug 10.


Improved intervention of atherosclerosis and cardiac hypertrophy through biodegradable polymer-encapsulated delivery of glycosphingolipid inhibitor.

Mishra S, Bedja D, Amuzie C, Foss CA, Pomper MG, Bhattacharya R, Yarema KJ, Chatterjee S.

Biomaterials. 2015 Sep;64:125-135. doi: 10.1016/j.biomaterials.2015.06.001. Epub 2015 Jun 3.


Cell Surface and Membrane Engineering: Emerging Technologies and Applications.

Saeui CT, Mathew MP, Liu L, Urias E, Yarema KJ.

J Funct Biomater. 2015 Jun 18;6(2):454-85. doi: 10.3390/jfb6020454. Review.


Identification of sialylated glycoproteins from metabolically oligosaccharide engineered pancreatic cells.

Tian Y, Almaraz RT, Choi CH, Li QK, Saeui C, Li D, Shah P, Bhattacharya R, Yarema KJ, Zhang H.

Clin Proteomics. 2015 Apr 11;12(1):11. doi: 10.1186/s12014-015-9083-8. eCollection 2015.


Metabolic glycoengineering bacteria for therapeutic, recombinant protein, and metabolite production applications.

Saeui CT, Urias E, Liu L, Mathew MP, Yarema KJ.

Glycoconj J. 2015 Oct;32(7):425-41. doi: 10.1007/s10719-015-9583-9. Epub 2015 May 1. Review.

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